Protein Info for AMB_RS12965 in Magnetospirillum magneticum AMB-1

Annotation: penicillin acylase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 803 transmembrane" amino acids 36 to 59 (24 residues), see Phobius details PF01804: Penicil_amidase" amino acids 75 to 791 (717 residues), 752.1 bits, see alignment E=4.6e-230

Best Hits

KEGG orthology group: K01434, penicillin amidase [EC: 3.5.1.11] (inferred from 100% identity to mag:amb2576)

Predicted SEED Role

"Penicillin acylase II precursor (EC 3.5.1.11)" (EC 3.5.1.11)

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.1.11

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2W445 at UniProt or InterPro

Protein Sequence (803 amino acids)

>AMB_RS12965 penicillin acylase family protein (Magnetospirillum magneticum AMB-1)
MPEHENGAKFKETAGKNSDNPDFARIGDSMSIWAKLANGVALVLLLGCSAMFVVVMGSLP
RIDGRHPVNGIQLKTTITRDSVGIPKIVADTRHDAYFAMGWVHAQDRMWQLETQRRLGAG
RLAEVVGEPGLASDRYMRTLGLYQAAERSLGALPEPTRSALQSYADGINAWLSYNTHRLP
PEFDLLRLKPEPWTPADSMVWQKIMAMTLAGNWHDDVLRAQLARTLDSKRMQELFPAYPA
DAPVTLATEGGKALLDLSTEALRPMPASNVWVVGGARTRSGKPLLAGDPHLAFRAPVLWY
LAEVEMPGLKLAGATVPGLPFHLIGHNGRIAWSFTSTQADTVDLFVEKLAGETGYRTPEG
AKPFLTRTETIKVKGGADVTLTVRETRHGPVISDLLPQAIAAKDEVVALAATALGHGDTS
VGALHALNQATDWPSFTKAVKDVQAPVLNIAYADTAGNIGFFTAGRIPVRKSGNGTVPMR
GWTGEGDWTGWVATAKLPQSLNPKSAVLINANNKVVGEKYPHLITASWPDGYRAARIRDL
LGERRGLTIEDMAAIQADAVSPQAIELKDLLTGIEFKDQHARDIAHRIAEWDGKADRDRS
EPLIFAAWMNRLNRAILADELKDNFPAFEQVRAPVLVDILTRRRHWCDDITTPEAESCDD
LIEGSLTKALADLEKAWGKDMKTWRWGAAHPARFAHPFLGKIPVLGDMANLQVPSDGDDF
TISRGTYTVEGDGAHFPQIHGAGLRVVFDLADLADSRFVIATGQSGNPLSRHYADMLPAW
SVNRLYRLGLDAKRSVLTLERGR