Protein Info for AMB_RS11555 in Magnetospirillum magneticum AMB-1

Annotation: MBL fold metallo-hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 283 transmembrane" amino acids 20 to 43 (24 residues), see Phobius details PF13483: Lactamase_B_3" amino acids 41 to 242 (202 residues), 46.5 bits, see alignment E=4.1e-16 PF12706: Lactamase_B_2" amino acids 71 to 243 (173 residues), 44.1 bits, see alignment E=1.8e-15

Best Hits

KEGG orthology group: K03476, L-ascorbate 6-phosphate lactonase [EC: 3.1.1.-] (inferred from 100% identity to mag:amb2285)

Predicted SEED Role

No annotation

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.1.1.-

Use Curated BLAST to search for 3.1.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2W4Y6 at UniProt or InterPro

Protein Sequence (283 amino acids)

>AMB_RS11555 MBL fold metallo-hydrolase (Magnetospirillum magneticum AMB-1)
MRYSWALGPRWSTHYQHGWIMTGLMAEITATPVAKGTLALWFLGQNGWMIKSPAGKVLAV
DPYLSNSCHPSRRGLDLDRRVPILVTPEALEADLLLCTHSHKDHADPATLCACARGGRVK
AFAGPGDTQAVFAAAGVAESQRGLTWPNHEIFLEDLKVTGTFALPTDAGDLTHMGFVIQV
DGGPSLWITGDTAWCDLLAEAGARHQPDAICLPINGGYANLSHWDAAELVRRVAPAQAIP
CHWDMFADNSCPPHLFEASLKVKEVRGVYRLPEHGRKMVIEPR