Protein Info for AMB_RS10340 in Magnetospirillum magneticum AMB-1

Annotation: BREX system Lon protease-like protein BrxL

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 675 TIGR02653: conserved hypothetical protein" amino acids 3 to 674 (672 residues), 1199.8 bits, see alignment E=0 TIGR02688: TIGR02688 family protein" amino acids 10 to 456 (447 residues), 633.4 bits, see alignment E=1.9e-194 PF20442: BrxL_N" amino acids 12 to 142 (131 residues), 176.2 bits, see alignment E=4.6e-56 PF13337: BrxL_ATPase" amino acids 153 to 465 (313 residues), 489.7 bits, see alignment E=4.2e-151 PF05362: Lon_C" amino acids 513 to 670 (158 residues), 47.8 bits, see alignment E=2.1e-16

Best Hits

KEGG orthology group: K01338, ATP-dependent Lon protease [EC: 3.4.21.53] (inferred from 100% identity to mag:amb2047)

Predicted SEED Role

"ATP-dependent protease La (EC 3.4.21.53)" in subsystem Proteolysis in bacteria, ATP-dependent (EC 3.4.21.53)

Isozymes

Compare fitness of predicted isozymes for: 3.4.21.53

Use Curated BLAST to search for 3.4.21.53

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2W5M4 at UniProt or InterPro

Protein Sequence (675 amino acids)

>AMB_RS10340 BREX system Lon protease-like protein BrxL (Magnetospirillum magneticum AMB-1)
MSDSLDDLLNSHFAGRVVRKDLTKLVKEGANVPVYVLEYLLGMYCASNDEVTIREGLESV
KKILAENYVRPDEAEKVKSKIRERGSYKVIDKVTVHLNEKRNVYQALLSNLGVKDAEMPD
HYVRQYEKLLVGGIWCIVTIQFYHEENQKSSPFIVSDLKPIQMPNMDMDELFEGRKAFDE
SQWIDVLVRSSGMEPTTLSERVKWHLLARMVPLVENNYNVCELGPRGTGKSHIYKEISPN
SILISGGQTTVANLFYNMGRRTVGLVGLWDCVAFDEVAGITFKEKDGVQIMKDYMASGSF
ARGKDSVSAYASMVFVGNINQPVDTLVKTSHLLAPFPEAMIDSAFFDRFHAYIPGWEIPK
MRPEFFTNQYGLIVDYLAEFFREMRKRTFGDAIDKFFKLGNNLNQRDTIAVRRTVSGLLK
LLYPHEEYDKDAVRRCLEYALESRRRVKEQLKKIGGMEFYDVHFSYIDIESMEEKWISVP
EQGGGKIIPEGPLKPGVLHTVATGAAAHLGLYRFETQVTAGNGKLTTSGLGSSSGAKEAV
KVAFDYFKANLTRVSGVSKAGDHDFHLHTVELHNTGAAKAMTLASFVAFCSAIIQKPLQS
QMVVLGDMSLGGSVVPVENLAECLQVAFDSGAKRILIPMSSAADIPTIPAELFAKFQTSF
YSDPVDAVFKALGVD