Protein Info for AMB_RS08515 in Magnetospirillum magneticum AMB-1

Annotation: aspartate aminotransferase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

Best Hits

Swiss-Prot: 50% identical to GATP3_SOLLC: Gamma aminobutyrate transaminase 3, chloroplastic (GABA-TP3) from Solanum lycopersicum

KEGG orthology group: None (inferred from 100% identity to mag:amb1684)

MetaCyc: 51% identical to gamma aminobutyrate transaminase (Solanum lycopersicum)
RXN-6902 [EC: 2.6.1.96]

Predicted SEED Role

"Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)" in subsystem Biotin biosynthesis (EC 2.6.1.62)

MetaCyc Pathways

biotin biosynthesis I (13/15 steps found)
biotin biosynthesis from 8-amino-7-oxononanoate I (4/4 steps found)
4-aminobutanoate degradation IV (1/3 steps found)

KEGG Metabolic Maps

Biotin metabolism

Isozymes

Compare fitness of predicted isozymes for: 2.6.1.62

Use Curated BLAST to search for 2.6.1.62 or 2.6.1.96

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2W6N7 at UniProt or InterPro

Protein Sequence (459 amino acids)

>AMB_RS08515 aspartate aminotransferase family protein (Magnetospirillum magneticum AMB-1)
MQTHASNRTIAEKDVDSVLHPYTNLKRHPEVGPLVITRGQGVRVYDEAGRDYIEGLAGLW
CTSLGWGEERLVEAAARQMRQLPFYHLFSHKTHDVGVELCARLLAMAPVPMSKVFLAGSG
SEANDTAIKLIHYRANALGTPDKKKIIAREKAYHGVTVATASLTGLVNNQRSFDLPIPGV
LRAACPHHYRFAKDGESEEDFSTRLAGELEAMILAEGPDTVAAFFAEPVMGAGGVIVPPA
GYFPKIQAVLDRYDVLLVVDEVICGFGRTGKMFGTETFGIRPDMMTLAKGLSSGYAPISA
LMVNERVYGPVAEESGRIGVFGHGYTYGGHPVSAAVALETLNIYAERDILAQVAEVGPVL
QDGLRALRGHPLVGEARGVGLIGAVELVADKANRAPFPPELAVGARVVAKAQAKGVILRA
MGDAVAFAPPLVISKADIAEMLRRFGLALDEAHGELGRG