Protein Info for AMB_RS08445 in Magnetospirillum magneticum AMB-1

Annotation: signal transduction protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 560 PF00563: EAL" amino acids 305 to 536 (232 residues), 187.7 bits, see alignment E=1.1e-59

Best Hits

KEGG orthology group: None (inferred from 100% identity to mag:amb1669)

Predicted SEED Role

"diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s)" in subsystem Bacterial hemoglobins

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2W6Q2 at UniProt or InterPro

Protein Sequence (560 amino acids)

>AMB_RS08445 signal transduction protein (Magnetospirillum magneticum AMB-1)
MGSGDASLVEKLKLQRDRFIAFAFAGADLLLEMNDEDVVTYSAGAGEALYGISDSELLGR
PLAEFIFQRDKDKFTDAIQRLRNSGRLDHTPLSMVGASGAVSRMRMAGIKLPQFPTGYHL
VLSRISPLATSENDQSGQTADPRVRFVDMVRQRLNEANRLGEDYTLTMFDLSASKFGGTE
PALLQSFFSTLHHALEGCSVRQSSAGALNERAFGLVHDQTVSSGDVQEKVNEVFRQFSGK
VKGASLKMHSASLEMDDSAMSEDDLGKALNFIINGFVRDSAKFAIKSLAEGAKVAVEDTL
VRVRNFRKMIRGDKLAFFFQPMVNVSTGTVLAYEAFGRIAHDKGFFAPSQIIPFATDVGV
IGEFDLMAVRKALAAMKAASDISALASIAVNVSGTSLGNPAFYHSLVKILEENKPVLARL
VLEITDAARIYNLDEARRLLARIKRLGVRLSLDDFGSGGAAFDILKILPADYVKIDRDYI
FDAREKRGRSVLRAMVSLTHDLGMTAIGECIEDSQMLAVLKDVGIEYAQGHFFSPPALDA
ARKIKYYKDHLKVAEPSAAE