Protein Info for AMB_RS07730 in Magnetospirillum magneticum AMB-1

Annotation: NUDIX hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 238 PF00293: NUDIX" amino acids 104 to 203 (100 residues), 38.5 bits, see alignment E=5.8e-14

Best Hits

KEGG orthology group: K01515, ADP-ribose pyrophosphatase [EC: 3.6.1.13] (inferred from 100% identity to mag:amb1530)

Predicted SEED Role

"ADP-ribose pyrophosphatase (EC 3.6.1.13)" in subsystem NAD and NADP cofactor biosynthesis global or Nudix proteins (nucleoside triphosphate hydrolases) (EC 3.6.1.13)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.6.1.13

Use Curated BLAST to search for 3.6.1.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2W741 at UniProt or InterPro

Protein Sequence (238 amino acids)

>AMB_RS07730 NUDIX hydrolase (Magnetospirillum magneticum AMB-1)
MPLTEGKSSTRRADYRRYRELVATRPELFDRPQGGISILLDEADIAAASEVVAKRNQSRG
LPAAASSVGVLVEDAYILMLRDAVRFPDGSLGTHNRVIYPNGARGVGVLPLLDGQIVLLK
VYRHAIGRSLLEIPRGSVEVGDSLEDTVLREIAEETGGAVIGTAHLGHSFCDTSLSNGGL
DYFLAELSGVGEPQLSEGIVDIVQVTPARFAEMVMAGEIKDIHAVNAFSLARLRGLLP