Protein Info for AMB_RS04860 in Magnetospirillum magneticum AMB-1

Annotation: IS110 family transposase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 342 PF01548: DEDD_Tnp_IS110" amino acids 7 to 148 (142 residues), 64.8 bits, see alignment E=8.1e-22 PF02371: Transposase_20" amino acids 214 to 292 (79 residues), 86.7 bits, see alignment E=1.1e-28

Best Hits

Swiss-Prot: 51% identical to TPF20_PSEAE: Probable family 20 transposase (PA0445) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K07486, transposase (inferred from 100% identity to mag:amb0949)

Predicted SEED Role

"Mobile element protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2W8S2 at UniProt or InterPro

Protein Sequence (342 amino acids)

>AMB_RS04860 IS110 family transposase (Magnetospirillum magneticum AMB-1)
MTEVSTIGFDLAKRVFQVHGVDGDGAVTIRRQLRRSEVVTFFAKLSPCVVGMEACASAHY
WARTLAKLGHEVRLIPPSRVKPYVKRGRKNDAADAAAIAEAVTRPHMEFVPVKSEEAQAV
LMLHRTRRLLVTQRTMLGNALRSHFAEYGIIEPEGQGGLARLVVCALDAPDAALPQAARE
AMAMLAAHVREIDSKIDALDHEILRWHRNDADSQRVASIPGIGPLIASAIVAAMGDPKRF
KTGRDFAAWLGLVPSQNSTGGKTVLGPITKAGDRYLRSLLVVGATGTLWRRRKEQGTWLA
GMMARGKTARQISVALANKMARTAWAILAKGGLYHEPAAQAA