Protein Info for AMB_RS02280 in Magnetospirillum magneticum AMB-1

Annotation: hybrid sensor histidine kinase/response regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 727 PF00512: HisKA" amino acids 120 to 185 (66 residues), 68.1 bits, see alignment E=1.1e-22 PF02518: HATPase_c" amino acids 232 to 347 (116 residues), 104.3 bits, see alignment E=1e-33 PF00072: Response_reg" amino acids 497 to 609 (113 residues), 101.9 bits, see alignment E=4.6e-33 PF01627: Hpt" amino acids 641 to 716 (76 residues), 35.1 bits, see alignment E=2.5e-12

Best Hits

KEGG orthology group: None (inferred from 100% identity to mag:amb0441)

Predicted SEED Role

"Chemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY" in subsystem Bacterial Chemotaxis or Flagellar motility or Two-component regulatory systems in Campylobacter

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2WA80 at UniProt or InterPro

Protein Sequence (727 amino acids)

>AMB_RS02280 hybrid sensor histidine kinase/response regulator (Magnetospirillum magneticum AMB-1)
MRDELARLRAALDKGEQERSDLEIELQAAIEHGDAIEAELALANDQMRAEIAERIRAEAK
LQRLLAALGEQKADLEMLVHTITQHSDEIDIEQELANEQLRLENERINLAKEQAESLAQA
KTEFVAVVSHEVRTPMNGLLGMTQLLLDTPLTQEQRDIAGTVMSSGRLLLNILDELLDLS
KIEAGKLQIEHLEVKVVDLVEESFGLMSMRATERGLAVAHAIAPDVPAMVTGDPSRLRQV
LLNLIGNAIKFTEKGSVTLTVTRVPVHRTGGEGLRFAVADTGIGIPEEARDQLFRRYVQA
AAWVSRKFGGTGLGLSICRQLVELMGGEIGVDSVAGQGSVFWFQIPLIPVAASPGRSRPA
HAPARLLLLEPEAPVRTALTTILAGWGIQVMEATKASAATLGRPGDVLLLGGRMALSEAQ
VLARNSGLAAIILSPLGTTPTTGETDAVAILPEPVREAALIRALDQFGAPGRAIGPGPAD
LPHRGQEAAQAGQSLTVLVVEDNPVNRRVAGGFLSRQGHTVLMAENGAQALEVIASHPVD
IILMDRHMPVMDGLQAVRALRAMPPPAGHLPVVALTAAATREEARECLDAGMNDFISKPF
TPEQLTEAIDRQMRGRLTADFDRAALVTLSERIGDDGLVEIIGDYRTVSQSLAEAIVRAA
TMRDGQALGEAAHSLSGCSGQLGLNGISGLCRAVEGALREGRLDDALAMAAQIPAAHARG
LAFLRDG