Protein Info for AMB_RS01650 in Magnetospirillum magneticum AMB-1

Annotation: ATPase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 886 PF01627: Hpt" amino acids 3 to 94 (92 residues), 60.7 bits, see alignment E=3.4e-20 PF02895: H-kinase_dim" amino acids 206 to 265 (60 residues), 59.4 bits, see alignment 9.7e-20 PF02518: HATPase_c" amino acids 313 to 452 (140 residues), 60.5 bits, see alignment E=5.1e-20 PF01584: CheW" amino acids 458 to 587 (130 residues), 86.5 bits, see alignment E=3.2e-28 amino acids 619 to 735 (117 residues), 33.6 bits, see alignment E=6.9e-12 PF00072: Response_reg" amino acids 764 to 875 (112 residues), 70.1 bits, see alignment E=4.6e-23

Best Hits

KEGG orthology group: K03407, two-component system, chemotaxis family, sensor kinase CheA [EC: 2.7.13.3] (inferred from 100% identity to mag:amb0326)

Predicted SEED Role

"Signal transduction histidine kinase CheA (EC 2.7.3.-)" in subsystem Bacterial Chemotaxis or Flagellar motility or Two-component regulatory systems in Campylobacter (EC 2.7.3.-)

Isozymes

Compare fitness of predicted isozymes for: 2.7.13.3, 2.7.3.-

Use Curated BLAST to search for 2.7.13.3 or 2.7.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2WAJ5 at UniProt or InterPro

Protein Sequence (886 amino acids)

>AMB_RS01650 ATPase (Magnetospirillum magneticum AMB-1)
MDDLLSEFLTETSESLSVLDIALVNLEQNPNDPQILGNIFRLVHTIKGTCGFLGLPRLEH
VAHAGENVLGKFRDGELEVTPDAVTLILQSIDRIKLILGHLEQNECEPEGSDEDLIERLN
AMAEGRAIGAPSAPPPPSPPMPVFEPVAAAPAPEPVAAAPEPEPEPEPEPVKASVPATTP
QPSPPAAAAAPPVPAGEAKESAVAAQTIRVNVELLENLMTLVSELVLTRNQLLQMVRGKD
DSEFATPLQRLSHITTDLQEGVMKTRMQPIGNAWAKLPRIVRDLAVEMNKKIDLQMLGAE
TELDRQVLELIKDPLTHMVRNSADHGLEGTEERKRVGKPEIGKIVLNAFHEGGHIIIEIS
DDGRGLNLDRIKQKAIQNGLATESELEALTPQQIYQFIFKAGFSTAEKVTSVSGRGVGMD
VVRTNIEKIGGTVELKSQPGKGSSFIIKIPLTLAIVSALIVECAVERFAIPQISVLELVR
VTANSEHGIEMINNAPVLRLRDRLLPLVSLKRLLKLAENDEEQQETFIVVTQVGTYTFGI
IVDRVFDTEEIVVKPVAPILRHISMFSGNTILGDGSVIMILDPNGIAGATGESGMMAGGT
RDAEAQTVRESHADLKTSLLVFRAGGDDLKAVPLALVARLEEIEVGEIEHSHGKPMVQYR
GHLMPLIAIDGIMNFRDEGRQPVLVFSDKDHTMGLVVDEIVDIVEDRLKVELSADNPGVI
GTAVIAGKATTIIDAGYYLPQAFGDWFGRNDKEFGNADFHAPRVLLVDDSPFFRNLLTPL
LSVAGYEVISVDGADKALQLRERGDEFDAIISDIEMPGMSGFEFAAAVRADGRWGTIPMV
ALSSHATEKDFERGRQVGFNDYIAKFDRDALLQTLASTIAASKGAA