Protein Info for AMB_RS01425 in Magnetospirillum magneticum AMB-1

Annotation: bifunctional aldolase/short-chain dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 679 PF00596: Aldolase_II" amino acids 31 to 226 (196 residues), 68.1 bits, see alignment E=2.4e-22 PF00106: adh_short" amino acids 431 to 612 (182 residues), 134.8 bits, see alignment E=6.8e-43 PF01370: Epimerase" amino acids 433 to 550 (118 residues), 24.4 bits, see alignment E=4.6e-09 PF08659: KR" amino acids 433 to 533 (101 residues), 34.7 bits, see alignment E=4.3e-12 PF13561: adh_short_C2" amino acids 440 to 672 (233 residues), 145.8 bits, see alignment E=4.3e-46

Best Hits

KEGG orthology group: None (inferred from 100% identity to mag:amb0281)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2WAP0 at UniProt or InterPro

Protein Sequence (679 amino acids)

>AMB_RS01425 bifunctional aldolase/short-chain dehydrogenase (Magnetospirillum magneticum AMB-1)
MKSLWSDADAESFVTRYAPEGVNRDLALRVYTTRLLGGDPRLVLHGGGNTSCKTTVTDLL
GETVEVLCVKGSGWDMGDIEPAGLPAVRLAPLLKLRRLDSLSDEDMVDYQRGNLMNSASP
NPSVETLLHGFLPHKFIDHTHSTAVLSLVDQPDGEALAREVYGTRMGYVPYIMPGFALAK
KAAEIYEQDPTVEGLILVKHGIFTFADNARTAYELMIEMVTLAEQRLEKGRKPLVAATGL
PKDPAPLAEVAPILRGLLANGPKRRILDFRTSNAIRAYVDGAEIGRYSQQGVVTPDHTIR
TKNWPVVLPAPEAGKTAEWAEAAQAAIESFEAKYHAYFSRNNQRLGNIKTELDPKPCVAL
VPGLGLFGIGASAKDAAIAADIAVNTVESITDAEAIGRFEPVGEADLFDLEYWSLEQAKL
GKAAEKPLARQVVVVTGGGSGIGAATAKAFAKEGAEVAVLDRDADAAAKAAKACGGKALG
IACDVTDPASVRAAFDRVAERFGGVDVVVSNAGAAWQGAVGEVDDSTLRASFELNFFGHQ
AVAQNAVRVFKAQGTGGALLFNASKQAVNPGKNFGPYGLPKAATLFLMKQYALDHGKDGI
RSNAVNADRIRSGLLTDDMIKSRSSARGLSEQDYMGGNLLGREVTAEDVADAFVWLAKAS
KVTACTVTVDGGNIEASLR