Protein Info for AMB_RS00915 in Magnetospirillum magneticum AMB-1

Annotation: indolepyruvate oxidoreductase subunit B

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 502 transmembrane" amino acids 374 to 392 (19 residues), see Phobius details PF01558: POR" amino acids 9 to 207 (199 residues), 63.4 bits, see alignment E=2.8e-21 PF20169: DUF6537" amino acids 245 to 453 (209 residues), 140.5 bits, see alignment E=7.2e-45

Best Hits

KEGG orthology group: K00180, indolepyruvate ferredoxin oxidoreductase, beta subunit [EC: 1.2.7.8] (inferred from 100% identity to mag:amb0180)

Predicted SEED Role

"Indolepyruvate oxidoreductase subunit IorB II (EC 1.2.7.8)" in subsystem Aromatic amino acid interconversions with aryl acids (EC 1.2.7.8)

Isozymes

Compare fitness of predicted isozymes for: 1.2.7.8

Use Curated BLAST to search for 1.2.7.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2WAZ1 at UniProt or InterPro

Protein Sequence (502 amino acids)

>AMB_RS00915 indolepyruvate oxidoreductase subunit B (Magnetospirillum magneticum AMB-1)
MSTPHPLCIVVAAMGGEGGGVLTDWIVEAAHASGLAVQSTSVPGVAQRTGATTYYVEIFP
TPLAELGDARPILALSPSLGEVDLIVATELMEAARCVTRGWSDPARTQLIASSHRVHAVA
EKMEMGDGRYDGDRLRAAIQAGSRHHLLFDMEQAAKSAGCIVNAVLLGAVAGSGLLPIAP
ETFEEQIVASAKAVESNLRGFRLGLQAARGEIPAASTASHKRPHAEVPGSELVAVQLGFL
PAAARALAEEGVKRLTAYQDARYAGLYVERLRALSQVSADEALLARVAKHLAVRMSFEDV
IHVARLKTDPARLERIRAEVSARPGQPVVVRDFLKPGLEEICALLPGVLARPILAAAHGG
GWAGKAAWGRQVNASGIFGFATLRLLAALKLWRRHSYRFHQEQAAIEDWLAALGDAARLS
PALGIEVAECARLIKGYGETWNRGSANFRRIREAVIIPAAAGRWSLDFALDAIANARAAA
LADPEGAGLDRTLAAIAERAAA