Protein Info for AMB_RS00400 in Magnetospirillum magneticum AMB-1

Annotation: UDP-N-acetylglucosamine 2-epimerase (hydrolyzing)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 390 TIGR03568: UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing" amino acids 2 to 364 (363 residues), 454.6 bits, see alignment E=1.1e-140 PF02350: Epimerase_2" amino acids 22 to 364 (343 residues), 308.4 bits, see alignment E=2.7e-96

Best Hits

KEGG orthology group: None (inferred from 100% identity to mag:amb0079)

MetaCyc: 52% identical to UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-idopyranose C2-epimerase (Escherichia coli O108)
5.1.3.-

Predicted SEED Role

"UDP-Bac2Ac4Ac hydrolyzing 2-epimerase NeuC homolog"

MetaCyc Pathways

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2WB92 at UniProt or InterPro

Protein Sequence (390 amino acids)

>AMB_RS00400 UDP-N-acetylglucosamine 2-epimerase (hydrolyzing) (Magnetospirillum magneticum AMB-1)
MKRICVVTGTRAEYGPLFWVLKEIDAHADLELQLVVTGMHLSPEYGSTWKTIEADGFAIA
AKVEMLLSGDTGVAIAKSMGLGTIGFADAFERLKPDIVVVWGDRFELMAAVQAAVVARIP
IAHIGGGDVTEGAFDDAIRHAISKMAHLHFPIIADSARRLRQLGEDPERIHLTGNASLDH
LRRTIFLERAEVETRLNFSLRPRNVLVTYHPVTLDPEEGRRGWAEMLAALESLGDEVGIV
MTAPNADNDSRELMVALEAFVGAHPNAILRTSLGSQLYMSTARLCDAVVGNSSSGLLEIP
SLGVATVNIGTRQKGRPRADSVIDCPPERAAIRAAMDRAMAMDCSAVVNPYGDGQSARRI
VQVLAGIEDFPALLHKSFVDLAGPGEAGEE