Protein Info for ABZR88_RS15930 in Mucilaginibacter yixingensis YX-36 DSM 26809

Annotation: TlpA disulfide reductase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 383 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details PF14289: DUF4369" amino acids 26 to 127 (102 residues), 46.2 bits, see alignment E=2e-15 PF00578: AhpC-TSA" amino acids 245 to 363 (119 residues), 87.5 bits, see alignment E=2.5e-28 PF08534: Redoxin" amino acids 246 to 371 (126 residues), 82.4 bits, see alignment E=1e-26 PF13098: Thioredoxin_2" amino acids 268 to 374 (107 residues), 35.2 bits, see alignment E=4.7e-12 PF13905: Thioredoxin_8" amino acids 269 to 362 (94 residues), 84.6 bits, see alignment E=1.8e-27

Best Hits

Predicted SEED Role

"thioredoxin family protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (383 amino acids)

>ABZR88_RS15930 TlpA disulfide reductase family protein (Mucilaginibacter yixingensis YX-36 DSM 26809)
MMKKFLFLLAALCPMLAAAQMQKSTFTVKGTVGSVIDSPARAYLLYQLGANRLLDSATIH
KGQFSITGDVIYPAQATVVIDKAGAGIAKLDTSADHLVFFVEKGVINLNSTDKIAKAQIT
GSKINDDNKVLGTKMNVVEKTAEQISADVAAAPPEKKNSPDFQNQIQARYRSLQDMAETT
LKDFIKTNPNSFLSLMAVGSLAKNPNANPQELGDMLASLSDELKTSEPAIGIKVALEKMK
SGAVIGMPAPDFTQNDINGAPVKLSSFKGKYVLVDFWASWCGPCRQENPNVVRAYNKYKT
KNFTILGVSLDRDKTAWQNAIKNDGLAWTQVSDLQYWNNAVAAQYQVTSIPQNFLIDPQG
KVIAKNLRGEELDAKLAELLGKI