Protein Info for ABZR88_RS11640 in Mucilaginibacter yixingensis YX-36 DSM 26809

Annotation: sodium-translocating pyrophosphatase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 752 transmembrane" amino acids 6 to 25 (20 residues), see Phobius details amino acids 61 to 79 (19 residues), see Phobius details amino acids 86 to 106 (21 residues), see Phobius details amino acids 135 to 159 (25 residues), see Phobius details amino acids 181 to 195 (15 residues), see Phobius details amino acids 250 to 263 (14 residues), see Phobius details amino acids 285 to 306 (22 residues), see Phobius details amino acids 318 to 342 (25 residues), see Phobius details amino acids 372 to 394 (23 residues), see Phobius details amino acids 415 to 439 (25 residues), see Phobius details amino acids 445 to 466 (22 residues), see Phobius details amino acids 511 to 533 (23 residues), see Phobius details amino acids 545 to 569 (25 residues), see Phobius details amino acids 610 to 629 (20 residues), see Phobius details amino acids 634 to 654 (21 residues), see Phobius details amino acids 706 to 723 (18 residues), see Phobius details TIGR01104: V-type H(+)-translocating pyrophosphatase" amino acids 10 to 725 (716 residues), 881.6 bits, see alignment E=2.4e-269 PF03030: H_PPase" amino acids 17 to 718 (702 residues), 883.2 bits, see alignment E=6.5e-270

Best Hits

Predicted SEED Role

"Pyrophosphate-energized proton pump (EC 3.6.1.1)" in subsystem Phosphate metabolism (EC 3.6.1.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.6.1.1

Use Curated BLAST to search for 3.6.1.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (752 amino acids)

>ABZR88_RS11640 sodium-translocating pyrophosphatase (Mucilaginibacter yixingensis YX-36 DSM 26809)
MNFLNNYLIYLIPFLGVVGILVMAAKSAWVSKQDAGEGDMTELSGYIAKGAMAFLRAEWK
VLSYFVVLAGILLAYSGTTVKTSSPVIAISFIIGAFLSAFAGYIGMRIATKANVRTTQAA
KTSLAQALKVSFTGGTVMGLGVAGLAIIGLGSLFIVFYQMYVVSQHGNVNGFEMEKALEV
LAGFSLGAESIALFARVGGGIYTKAADIGADLVGKVEAGIPEDDVRNPATIADNVGDNVG
DVAGMGADLFGSYVATMLATMVLGREIVGADGKSLVDNFGGISPVLLPMLIAGLGLIFSI
VGAAFVRIKNEEDSVQNALNIGNWTSIILTAVATFFVVRWMLPAGDLHLIRDTMPGTTTL
KEGVKQFDKTGVYLSIIVGLVVGTLMSIITEYYTAMGKRPVISITQQSATGHATNIIGGL
AIGMESTVLPILVLAGGIYGSYHFAGLYGVAIAAAGMMATTAMQLAIDAFGPIADNAGGI
AEMSRLPEEVRHRTDNLDAVGNTTAATGKGFAIASAALTSLALFAAFVGVAGIDHIDIYK
ADVLAGLFVGGMIPFIFSSLAISAVGRAAMAMVHEVRRQFREIPGIMEHKAKPEYEKCVA
ISTQASIREMVAPGLIAIITPIIIGFTFGPEVLGGLLAGVTVSGVLMGMFQSNAGGAWDN
AKKSFEKGVEINGEVYKKGSEPHKAAVTGDTVGDPFKDTSGPSMNILIKLMSIVSLVIAP
HLNHEVRHNERLQDEINQHSQTVHVMKVDKKV