Protein Info for ABZR88_RS11000 in Mucilaginibacter yixingensis YX-36 DSM 26809

Annotation: reverse transcriptase/maturase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 604 PF00078: RVT_1" amino acids 88 to 234 (147 residues), 93.2 bits, see alignment E=2.8e-30 amino acids 293 to 362 (70 residues), 30.2 bits, see alignment E=5.4e-11 PF01348: Intron_maturas2" amino acids 396 to 508 (113 residues), 40.1 bits, see alignment E=5.3e-14 PF21368: AI2M-like_HNH" amino acids 550 to 595 (46 residues), 81.1 bits, see alignment 6.8e-27

Best Hits

KEGG orthology group: None (inferred from 58% identity to sne:SPN23F_12790)

Predicted SEED Role

"Retron-type RNA-directed DNA polymerase (EC 2.7.7.49)" (EC 2.7.7.49)

Isozymes

Compare fitness of predicted isozymes for: 2.7.7.49

Use Curated BLAST to search for 2.7.7.49

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (604 amino acids)

>ABZR88_RS11000 reverse transcriptase/maturase family protein (Mucilaginibacter yixingensis YX-36 DSM 26809)
MRSPEKVLNSLTEHSSDLNYKFERLYRLLFNEEMYYTAYQNIYSKVGNMTAGTDGTTIDG
MSISRVKRLIATLQNETYQPAPSKRIYIAKKNGKKRPLGIPTFIDKLLQEVIRMILNAIY
DGSFENTSHGFRPERSCHTALTKVQKTFTGAKWFIEGDIKGFFDNINHDVLIHVLGERIA
DERFIRLVRKFLNAGYVEDWVYHRSYSGTPQGGIISPILANIYLDKLDKYIKNYISQFDI
GTSRKLNPVLRQLVLKKHRLVKKLKIEKDENVRKQLIEQIKGIVKERQKYPPMDDMDKGF
RKLKYVRYADDFLIGIIGSKDDCRKVKEDIKAFLNDTLKLELSDEKTLITNANCHATFLG
YDVFVRKSNNTLTDKTGNPIRCFNSKVVLYVTTEVMRNKLLEYKALKITTPNKKEVWRGK
SRGNMIGFDALEIITQYNAEILGFYNYYSIANNSHIINSFYYIMRYSMYSTYASKYRSTI
SKLMYKYRVNKTFSIPYTNKKGQTKYRPLYNGGFKRKTPTYDSEVDTIAKTVTYTGGRNS
LSDRLKARICEYCEATDDIEMHHVRKLKDLKGKTEWEKKMIARRRKTLAVCSTCHDKLHA
GKLD