Protein Info for ABZR88_RS09800 in Mucilaginibacter yixingensis YX-36 DSM 26809
Annotation: DNA-3-methyladenine glycosylase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 45% identical to 3MGH_CYTH3: Putative 3-methyladenine DNA glycosylase (CHU_1611) from Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469)
KEGG orthology group: K03652, DNA-3-methyladenine glycosylase [EC: 3.2.2.21] (inferred from 57% identity to phe:Phep_2041)Predicted SEED Role
"DNA-3-methyladenine glycosylase II (EC 3.2.2.21)" in subsystem DNA Repair Base Excision (EC 3.2.2.21)
Isozymes
Compare fitness of predicted isozymes for: 3.2.2.21
Use Curated BLAST to search for 3.2.2.21
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (207 amino acids)
>ABZR88_RS09800 DNA-3-methyladenine glycosylase (Mucilaginibacter yixingensis YX-36 DSM 26809) MANSFSKIPAAFYQNPNVVEVARNLIGKYLFTRLDGLVTGGYIVETEAYNGPIDRASHAY GNKRTPRTETMFMPGGVAYIYLCYGIHEMLNIVVSVEDEPLAVLIRAIDPAIGLDVMQSR RNMAVIKPNITMGPGSVAKALGISRKINAISLQSDTLWLEDRGLTFTDDQIAVVPRIGVD YAKEDALLPYRFYVKGNPYVSRPVKGK