Protein Info for ABZR88_RS09435 in Mucilaginibacter yixingensis YX-36 DSM 26809

Annotation: bestrophin family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 309 transmembrane" amino acids 20 to 37 (18 residues), see Phobius details amino acids 43 to 62 (20 residues), see Phobius details amino acids 207 to 226 (20 residues), see Phobius details amino acids 232 to 250 (19 residues), see Phobius details PF01062: Bestrophin" amino acids 12 to 281 (270 residues), 185 bits, see alignment E=1.1e-58

Best Hits

KEGG orthology group: K08994, putative membrane protein (inferred from 58% identity to phe:Phep_3670)

Predicted SEED Role

"protein of unknown function UPF0187"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (309 amino acids)

>ABZR88_RS09435 bestrophin family protein (Mucilaginibacter yixingensis YX-36 DSM 26809)
MLLKKNVPFSYVFGKIKMEMIFLTIYSTAVYAAHSYFKLQGISIPLAIPGILGTIISLLL
AFRSNQAYDRWWEARTLWGAIVNDSRSFARQVLSFIDNAYGDADKQQLKERMIKRQMAWC
HALSHHLRGQNAQQGLGKYLSDDEYRALNGIKHVPVALMESHADDLRIAMRMNWINEYQQ
VALDETLTRFSNAMGGCERIKNTVFPVTYSFYIHVLVLLFVILMPFGLTEFFGIFQIPLV
VAISSSLFLIEKMAIHLQDPFENKPTDTPTTTISRNIERDLNQMLKNETSTEADKTSTVA
GTNAVFYVL