Protein Info for ABZR88_RS00225 in Mucilaginibacter yixingensis YX-36 DSM 26809

Annotation: RNA methyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 458 PF17125: Methyltr_RsmF_N" amino acids 7 to 88 (82 residues), 74.5 bits, see alignment E=1.2e-24 PF01189: Methyltr_RsmB-F" amino acids 106 to 296 (191 residues), 135.1 bits, see alignment E=3.9e-43 PF13636: Methyltranf_PUA" amino acids 404 to 453 (50 residues), 62 bits, see alignment 6.7e-21

Best Hits

Predicted SEED Role

"tRNA and rRNA cytosine-C5-methylases"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (458 amino acids)

>ABZR88_RS00225 RNA methyltransferase (Mucilaginibacter yixingensis YX-36 DSM 26809)
MSDIVFPGKFIESISNAPGFDAQNFVETHQNLPAPTSIRINPSKYSGQQPGVEVPWCPEG
FYLESRPSFTFDPLFHAGCYYVQEASSMFITHIYNSIRGEMDEPIRALDLCAAPGGKSTL
LSSALNQDDLLVANEIIKTRVPILTDNLTRWGRSNTIVTNNDPRDYGRVKGFFDLILVDA
PCSGSGMFRKEPEAMQEWSVDNVNLCQQRQERILADVYPALREDGYLIYSTCSYSEQENE
QVLDWLCTEFGMESVRIPVEQDWGVVESQSTEHKAWGYRFYPGKVQGEGLFAACLRKTES
SGETKAFKKKDQGKPDYKSIDLLKPYIKEPANYYFFKLNDDWLAIDKIHREDLETLQQYL
YIKKSGVRLGSLAGKDLVPDHELAMSLMLDRDQIQQTELSREQAISYLRRDEIKDLDLSQ
KGWNLMCFEGHPLGWAKLLPNRVNNYYPKEMRILSTGS