Protein Info for ABIE41_RS21990 in Bosea sp. OAE506

Annotation: D-TA family PLP-dependent enzyme

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 360 PF01168: Ala_racemase_N" amino acids 21 to 235 (215 residues), 69.4 bits, see alignment E=3.8e-23 PF14031: D-ser_dehydrat" amino acids 251 to 342 (92 residues), 74.7 bits, see alignment E=7.8e-25

Best Hits

KEGG orthology group: None (inferred from 74% identity to rpx:Rpdx1_3332)

Predicted SEED Role

"Type III PLP / low-specificity D-threonine aldolase" in subsystem Serine-glyoxylate cycle or Threonine degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (360 amino acids)

>ABIE41_RS21990 D-TA family PLP-dependent enzyme (Bosea sp. OAE506)
MRYDTLKDEIARTYGTPAVVIDLDKVEANIARLQAVCDAKGVANRPHIKTHKSPELARLQ
IEAGARGITCQKLGEAEVMADGGIDDILISYNILGEQKLGRLGHLQRRVRMIVAADNPVT
IAGLPQAAEIAGRDLEVVVECDTGRQRAGVETPGEAVELAKLIAGSKGLRFAGFLMYPPE
DGWARTQVFLDTANQGLRDAGLEASIVSTGGSPNIPHIGELKGATEHRAGTSIFNDRMQV
AAGVASLEDCALTVYATVVSRAGPERGILDSGSKTLTSDSGGLNGHGHILEYPAARIAKF
AEEHGFLDLSASNDRPGVGEIVRVVPNHVCVVVNMVDRLVTVRGDRLVGELPVAARGKLV