Protein Info for ABIE41_RS20530 in Bosea sp. OAE506

Annotation: Gfo/Idh/MocA family oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01408: GFO_IDH_MocA
  • amino acids 6 to 122 (117 residues), 87.4 bits, E=1.9e-28
• PF22725: GFO_IDH_MocA_C3
  • amino acids 134 to 254 (121 residues), 80.1 bits, E=2.1e-26
• PF02894: GFO_IDH_MocA_C
  • amino acids 140 to 330 (191 residues), 57.6 bits, E=2.5e-19

Best Hits

KEGG orthology group: None (inferred from 50% identity to smk:Sinme_4777)

Predicted SEED Role

"Gluconokinase (EC 2.7.1.12) / oxidoreductase domain" in subsystem D-gluconate and ketogluconates metabolism or Entner-Doudoroff Pathway (EC 2.7.1.12)

MetaCyc Pathways

• L-idonate degradation (3/3 steps found)
• D-gluconate degradation (1/1 steps found)
• sorbitol biosynthesis II (2/3 steps found)
• ketogluconate metabolism (4/8 steps found)

KEGG Metabolic Maps

• Pentose phosphate pathway

Isozymes

Compare fitness of predicted isozymes for: 2.7.1.12

Use Curated BLAST to search for 2.7.1.12

Protein Sequence (342 amino acids)

>ABIE41_RS20530 Gfo/Idh/MocA family oxidoreductase (Bosea sp. OAE506)
MTRRIGLAIIGLGPASLPHSKSLLDLAERADVRFAVSRSPERAATYARDFSFPTSTDLDA
VLADPSVDAAIVLTPPSSHLEVSRRCLEAGKHVLVEKPLELTSARGAELVAAARATGKVF
GVVLQHRFRPASLRLNAALDGGELGGIEAAFLQVPWWRPQAYYDEPGRGTLARDGGGVLL
TQAIHSLDLFRSLVGVSKVVAAQARTTGLHRMETEDYVSALLETDSGAPATLVTTTAAYP
GHPERIEIIGTKGFAALVGGRLELSFLDGRKEVVEAEGSTGSGANIMDFPHDAHRAVIGD
FLDAIVEGRDPVVTGEEALASQHLVDAILKTAGWPAARGTGG