Protein Info for ABIE41_RS17800 in Bosea sp. OAE506

Annotation: DNA repair protein RadA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 465 TIGR00416: DNA repair protein RadA" amino acids 1 to 447 (447 residues), 541 bits, see alignment E=1.1e-166 PF18073: Rubredoxin_2" amino acids 8 to 35 (28 residues), 34.7 bits, see alignment (E = 2.8e-12) PF06745: ATPase" amino acids 75 to 160 (86 residues), 43 bits, see alignment E=9e-15 PF13481: AAA_25" amino acids 87 to 224 (138 residues), 59.8 bits, see alignment E=7.5e-20 PF13541: ChlI" amino acids 339 to 429 (91 residues), 31.3 bits, see alignment E=4.1e-11

Best Hits

Swiss-Prot: 68% identical to RADA_BRUA2: DNA repair protein RadA (radA) from Brucella abortus (strain 2308)

KEGG orthology group: K04485, DNA repair protein RadA/Sms (inferred from 72% identity to mno:Mnod_4631)

Predicted SEED Role

"DNA repair protein RadA" in subsystem DNA repair, bacterial

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (465 amino acids)

>ABIE41_RS17800 DNA repair protein RadA (Bosea sp. OAE506)
MAKRGPTYTCQACGAVYHRWQGKCDACGTWSSLSEEAQAAPVPGARGASGGRARGRVFAL
EGLKGETQDAPRIVSGIGELDRVTGGGFVPGSVLLIGGDPGIGKSTLLMQACAALASAGR
RVVYVSGEESTGQVRLRAERMGLSEAPVELAAETNVEDIVATLSQGSRPALVVIDSIQTM
WSGEVESAPGTVTQVRGSAQALIRYAKTSGTCMILVGHVTKDGQIAGPRVVEHMVDAVLS
FEGEGAHAFRILRGQKNRFGATDEIGVFEMTGKGLSEVSNPSALFLAGRDQAAPGAAVFA
GIEGTRPVLVEIQALVAPTSLGTPRRAVVGWENSRLSMVLAVLETHGGLRLGQHDVYLNV
AGGLRVNEPAADLAVAAALVSSLTGAILPSESVYFGEIALSGAIRPVSVAAARLREASKL
GFEAALMPSGGADAGDGGGLSLRRFGHVTELVADIAARAPRRDVK