Protein Info for ABIE41_RS12765 in Bosea sp. OAE506

Annotation: class I SAM-dependent methyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 208 PF01209: Ubie_methyltran" amino acids 23 to 147 (125 residues), 40.5 bits, see alignment E=8.1e-14 PF05175: MTS" amino acids 25 to 143 (119 residues), 24.1 bits, see alignment E=1e-08 PF13489: Methyltransf_23" amino acids 25 to 166 (142 residues), 54.7 bits, see alignment E=4e-18 PF02390: Methyltransf_4" amino acids 37 to 97 (61 residues), 29.4 bits, see alignment E=2.2e-10 PF13847: Methyltransf_31" amino acids 37 to 156 (120 residues), 54.8 bits, see alignment E=3.8e-18 PF13649: Methyltransf_25" amino acids 38 to 138 (101 residues), 67.6 bits, see alignment E=5.2e-22 PF08241: Methyltransf_11" amino acids 39 to 141 (103 residues), 54.1 bits, see alignment E=8.2e-18 PF08242: Methyltransf_12" amino acids 39 to 140 (102 residues), 62.3 bits, see alignment E=2.4e-20

Best Hits

KEGG orthology group: K13623, S-adenosylmethionine-diacylgycerolhomoserine-N-methlytransferase (inferred from 58% identity to oan:Oant_1727)

MetaCyc: 54% identical to diacylglycerolhomoserine N,N,N-trimethyltransferase (Cereibacter sphaeroides)
2.1.1.M42 [EC: 2.1.1.M42]

Predicted SEED Role

"Mlr1575 protein"

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.1.1.M42

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (208 amino acids)

>ABIE41_RS12765 class I SAM-dependent methyltransferase (Bosea sp. OAE506)
MDAIYRHQRHIYDASRKFYLLGRDRLIDELAPPERGSVLEIGCGTGRNLIRIAQAYPGRA
CFGLDVSSAMLETARRSVARAGLTDRIGLAQADATDFDPLALFGRAGFDRIVISYALSMI
PPWQGVVEEALRRLAPGGELHIVDFGDQHALPGAFRTLLNRWLALFHVTPRRDLAAVLAG
CATRAGATLQARSLHRGYAALAVLRRAG