Protein Info for ABIE40_RS28750 in Rhizobium sp. OAE497

Annotation: chemotaxis protein CheA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 653 PF01627: Hpt" amino acids 3 to 89 (87 residues), 43.1 bits, see alignment E=8.3e-15 PF02895: H-kinase_dim" amino acids 266 to 332 (67 residues), 41.5 bits, see alignment E=2.9e-14 PF02518: HATPase_c" amino acids 383 to 519 (137 residues), 58.4 bits, see alignment E=1.8e-19 PF01584: CheW" amino acids 525 to 652 (128 residues), 78.5 bits, see alignment E=8e-26

Best Hits

Predicted SEED Role

"Signal transduction histidine kinase CheA (EC 2.7.3.-)" in subsystem Bacterial Chemotaxis or Flagellar motility or Two-component regulatory systems in Campylobacter (EC 2.7.3.-)

Isozymes

Compare fitness of predicted isozymes for: 2.7.3.-

Use Curated BLAST to search for 2.7.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (653 amino acids)

>ABIE40_RS28750 chemotaxis protein CheA (Rhizobium sp. OAE497)
MDELIAQFAIEARELVQQASEDLLSLEANPRQRESLESAFRAIHTLKGSVGLFDFGPMLG
ILHQAEDLLSQARAGKIVVDATLIDPLLAVIEWVDSSIEGISETGRLSEAQEKQAPRLLR
LVSGEMTERDAGETALAPTAIPDWALTLRQQVPGADAGTTLIAIRYEPHPECFFNGDDPL
ATISRLSDLRHLALSLREPRPAPQDYDPFRCNLLIEAVSGGSLAEAEGVFRLIPDQVKLF
TLPGAPGEQATAQPEASPDRAADRQSTTMRVDSARIDKLVEIAGELITAKNGLVPLADEA
RSHGNGQLARRILANHHEFERLVASLYSAVTQARMIPLEHTFRRFPRLVRETSARLGKAL
DLIIEGESVEADREIVENLFEPLLHLIRNGLDHGIEPEADRLKQSKPARARLLLRARQRG
DQIEIDVADDGRGMDPQRVRATAIDRGLISEGQASALSDRDVLQFVFAPGFSTASSVSDL
SGRGVGLDAVQSSVRRLGGTLELQSTVGAGTSFVLKLPVSFSMTQLMVVQVGDERYGIPI
SDVIETQKLPASAVQSVRAGKAFVLRNRTIPLLHLGELLQSQLPSAHSNDLKVLIVQAGE
DQIGVAVDAIAERAETLTRPLAGLLQGVPGIAGTTLLGDGKVLLVLNMEELVK