Protein Info for ABIE40_RS18765 in Rhizobium sp. OAE497

Annotation: amino acid ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 226 transmembrane" amino acids 20 to 46 (27 residues), see Phobius details amino acids 58 to 78 (21 residues), see Phobius details amino acids 84 to 103 (20 residues), see Phobius details amino acids 187 to 207 (21 residues), see Phobius details TIGR01726: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family" amino acids 15 to 110 (96 residues), 100.9 bits, see alignment E=2.3e-33 PF00528: BPD_transp_1" amino acids 34 to 216 (183 residues), 89.6 bits, see alignment E=1.1e-29

Best Hits

Swiss-Prot: 57% identical to TCYB_BACSU: L-cystine transport system permease protein TcyB (tcyB) from Bacillus subtilis (strain 168)

KEGG orthology group: K02029, polar amino acid transport system permease protein (inferred from 91% identity to rle:RL4635)

MetaCyc: 56% identical to cystine ABC transporter membrane subunit (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-290 [EC: 7.4.2.12]; 7.4.2.12 [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]

Predicted SEED Role

"Cystine ABC transporter, permease protein"

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (226 amino acids)

>ABIE40_RS18765 amino acid ABC transporter permease (Rhizobium sp. OAE497)
MPHWLQLMVESLPTLLWGGIKFTIPLTLLSFVFGLALGLLTAVARLFGPAPFRAIARFYV
WIIRGTPLLVQLFVIFYGLPSIGILLDAFPAALIGFTLNIGAYSSEIIRAVISSVPKGQW
EAAYSIGMNWRQAMTRTILPQAARVAVPPLSNTFISLVKDTSLAAAITVPELFQAAQRIV
ATTYEPLILYIEAALIYLVLSSVLSALQVRLERRFARYGGTLEANS