Protein Info for ABIE40_RS15125 in Rhizobium sp. OAE497

Annotation: sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 359 PF00005: ABC_tran" amino acids 19 to 161 (143 residues), 120.9 bits, see alignment E=1.3e-38 PF17912: OB_MalK" amino acids 235 to 284 (50 residues), 48.7 bits, see alignment 2.4e-16 PF08402: TOBE_2" amino acids 278 to 343 (66 residues), 28.3 bits, see alignment E=3.2e-10

Best Hits

Swiss-Prot: 57% identical to UGPC_BURTA: sn-glycerol-3-phosphate import ATP-binding protein UgpC (ugpC) from Burkholderia thailandensis (strain ATCC 700388 / DSM 13276 / CIP 106301 / E264)

KEGG orthology group: K05816, sn-glycerol 3-phosphate transport system ATP-binding protein [EC: 3.6.3.20] (inferred from 57% identity to bte:BTH_I3018)

MetaCyc: 51% identical to sn-glycerol 3-phosphate ABC transporter ATP binding subunit (Escherichia coli K-12 substr. MG1655)
ABC-34-RXN [EC: 7.6.2.10]; 7.6.2.10 [EC: 7.6.2.10]

Predicted SEED Role

"Glycerol-3-phosphate ABC transporter, ATP-binding protein UgpC (TC 3.A.1.1.3)" in subsystem Glycerol and Glycerol-3-phosphate Uptake and Utilization (TC 3.A.1.1.3)

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.20

Use Curated BLAST to search for 3.6.3.20 or 7.6.2.10

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (359 amino acids)

>ABIE40_RS15125 sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC (Rhizobium sp. OAE497)
MAEIQFSNITKSFGATQVLHSLNLQIERGAFAVILGPSGCGKSTLLRLLAGLERASGGEI
EIAGRRVETLEPRQRDVAMVFQNYALYPHMSVAQNLGYSLVVAGVKRAEIDRRVAEVART
LQLEDYLQRKPGQLSGGQRQRVAMGRAIIREPKVFLFDEPLSNLDAKLRTQMRLEIKRLH
RKQGVTSLFVTHDQIEAMTLADILIVMNKGRIEQIGKPADIYERPATVFVASFLGSPPMN
LIPAVVDDSGCGVVLGGEMRIPLGGAVPAAPGSEIVAGIRPEHVQIGRGANLPVEFVEEL
GNGRQVHLRIGQTGMAALLPASDKQAVGTTLPVSLPSEHLHFFGSDGRLMELQPKSAAA