Protein Info for ABIE40_RS06575 in Rhizobium sp. OAE497

Annotation: RNA degradosome polyphosphate kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 734 TIGR03705: polyphosphate kinase 1" amino acids 31 to 706 (676 residues), 945 bits, see alignment E=1.2e-288 PF13089: PP_kinase_N" amino acids 32 to 136 (105 residues), 121.4 bits, see alignment E=5.1e-39 PF02503: PP_kinase" amino acids 146 to 322 (177 residues), 181.3 bits, see alignment E=4e-57 PF17941: PP_kinase_C_1" amino acids 351 to 515 (165 residues), 253.4 bits, see alignment E=2e-79 PF13090: PP_kinase_C" amino acids 522 to 700 (179 residues), 206.9 bits, see alignment E=4e-65

Best Hits

Swiss-Prot: 66% identical to PPK1_RHOPT: Polyphosphate kinase (ppk) from Rhodopseudomonas palustris (strain TIE-1)

KEGG orthology group: K00937, polyphosphate kinase [EC: 2.7.4.1] (inferred from 93% identity to ret:RHE_CH01491)

Predicted SEED Role

"Polyphosphate kinase (EC 2.7.4.1)" in subsystem High affinity phosphate transporter and control of PHO regulon or Phosphate metabolism or Purine conversions (EC 2.7.4.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.4.1

Use Curated BLAST to search for 2.7.4.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (734 amino acids)

>ABIE40_RS06575 RNA degradosome polyphosphate kinase (Rhizobium sp. OAE497)
MDSAVAEHQEPKPEASSAVPPLAELLQSPERFINREFSWLQFNRRVLEETLNTEHPLLER
VRFLSISAANLDEFFMVRVAGLEAQVRQNIAVRTPDGKTPAEQLDAILQEIDNLQMEQQA
SLAVLQQYLAREDILIVRPGALSDTDRQWLATEFEQAIFPVLTPLSIDPAHPFPFIPNLG
FSIGLQLASKHGREPMTALLRLPPALDRFVRLPDDGNTIRYITLEDVANIFIHRLYPGYE
VQGSGTFRIIRDSDIEVEEEAEDLVRFFETALKRRRRGKVIRIETDSEMPASLRHFVVQA
LSVPENRIAVLPGLLALNTLSEITKAPRDDLRFPPYNARFPERVREHAGDCFAAIREKDM
VVHHPYESFDVVVQFLLQAARDPDVLAIKQTLYRTSNDSPIVRALIDAAESGKSVTALVE
LKARFDEEANIRWARDLERAGVQVVFGFIELKTHSKMSLVVRREEGKLRSYCHLGTGNYH
PITAKIYTDLSFFTCNPVIAHDMANIFNFITGYGEPEESMKLAVSPYTLRSRILRHIDEE
IMHAKNGAPAAIWMKMNALVDPEIIDALYTASHAGVEIDLVVRGICCLRPQVPGLSENIR
VKSIVGRFLEHSRIFCFGNGYGLPSDKALVYIGSADMMPRNLDRRVETLVPLTNPTVKEQ
VLSQIMLGNIIDNQQSYEILPDGTSRRMEVRKGEEPFNAQQYFMTNPSLSGRGEALKSSA
PKLIAGLLSGRTKR