Protein Info for ABIE40_RS02015 in Rhizobium sp. OAE497

Annotation: HAMP domain-containing sensor histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 501 transmembrane" amino acids 33 to 54 (22 residues), see Phobius details amino acids 181 to 202 (22 residues), see Phobius details PF02518: HATPase_c" amino acids 372 to 486 (115 residues), 76.2 bits, see alignment E=1.4e-25

Best Hits

KEGG orthology group: None (inferred from 85% identity to rlg:Rleg_0099)

Predicted SEED Role

"Sensor histidine kinase in cluster with mercury reductase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (501 amino acids)

>ABIE40_RS02015 HAMP domain-containing sensor histidine kinase (Rhizobium sp. OAE497)
MPVQDQSGISANVTMAAGGERPAGWLSGLSGKLLWMIVLFIMLAEVLIFFPSIASMRIRW
LDDKLNTAAAAAIVIDGLQPVELPRSVQKETLEATGTKAIVLRKDGTSRLLAMSEMPTSV
DEQYDLTKVTPVSAICDALDTLIFGGNRMIRVYGPVGDTATGVEVVMKDRALRNAMFVYA
RNVLLLSILISLFTATLVFFVINRILIRPIRNLTGSMQDFSADPENPQNVFVGEGGRDEL
AVAGRHLTSMQVELQKTLKQQKNLAALGLAVSKINHDMRNILASAQLMSDRLVDVDDPMV
KSFAPKLLRTIDRAVGYTTAVLSYGQASESAPRRRRIRLYELTQDVRDMLAIDPASGVEF
VEQMSTDLEIDGDSEQLFRVIHNLCRNALQALMMPGELGMDGIKRITVSGQRVGSVVSII
VDDTGPGMPLKARQNLFTAFRGSARSGGTGLGLTIARELVLAHGGTIALVEKPAAGTQFR
IEIPDRPVSLDDYRSRSHAEK