Protein Info for ABID97_RS28505 in Variovorax sp. OAS795

Annotation: xanthine dehydrogenase family protein molybdopterin-binding subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01315: Ald_Xan_dh_C
  • amino acids 22 to 132 (111 residues), 101.6 bits, E=4.8e-33
• PF02738: MoCoBD_1
  • amino acids 169 to 405 (237 residues), 234.3 bits, E=1.7e-73
• PF20256: MoCoBD_2
  • amino acids 442 to 697 (256 residues), 199.6 bits, E=1.2e-62

Best Hits

KEGG orthology group: None (inferred from 57% identity to rpb:RPB_4416)

Predicted SEED Role

"Xanthine dehydrogenase, molybdenum binding subunit (EC 1.17.1.4)" in subsystem Purine Utilization (EC 1.17.1.4)

MetaCyc Pathways

• purine nucleotides degradation I (plants) (10/12 steps found)
• adenosine nucleotides degradation I (7/8 steps found)
• guanosine nucleotides degradation II (4/4 steps found)
• superpathway of guanosine nucleotides degradation (plants) (5/6 steps found)
• adenosine nucleotides degradation II (4/5 steps found)
• guanosine nucleotides degradation I (3/4 steps found)
• guanosine nucleotides degradation III (3/4 steps found)
• inosine 5'-phosphate degradation (3/4 steps found)
• purine nucleotides degradation II (aerobic) (8/11 steps found)
• ureide biosynthesis (5/7 steps found)
• superpathway of purines degradation in plants (12/18 steps found)
• purine nucleobases degradation II (anaerobic) (15/24 steps found)
• caffeine degradation III (bacteria, via demethylation) (2/7 steps found)
• caffeine degradation IV (bacteria, via demethylation and oxidation) (2/10 steps found)
• theophylline degradation (1/9 steps found)

KEGG Metabolic Maps

• Purine metabolism

Isozymes

Compare fitness of predicted isozymes for: 1.17.1.4

Use Curated BLAST to search for 1.17.1.4

Protein Sequence (766 amino acids)

>ABID97_RS28505 xanthine dehydrogenase family protein molybdopterin-binding subunit (Variovorax sp. OAS795)
MHSHPKLPLHQEPRADYLQKVTGTAIFASDVEVPGMLQGKILRSTVPHARIRSIDTSAAL
AMPGVVAVLTGADMKNLPGTANRWGLYLRDREVIAIDKVRYVGDPVAAVAAIDEVTAEEA
VDAIVVEYDPLPFVTTAREAMAEGAELVHQDMDKLKDFYFRGEASPVEGTNIFQHWKYSS
GDVDQAFVAAARVFEDTFTFPMVFHFAMEPHVSIADWKPHALEIWSGGQTPTAIARVCSE
TLGVPLACVRVHSPYIGGGFGGKASVKIDPLVAALSWKARAPVRVCLSIAESMLTCRRLD
AEITLKTAVDQTGRITAKSIKAVLNGGAFADTGPAIAIKAAIRAIGPYHIPNLQLESYGV
YTNTVPGAAFRSIGGPQAVWATESQMDIMADALGVDPIEFRMFNMADKGQIIKPDLRPLD
VDMRNSLRKAVGALEALPAMTAQRRRGRGVAVGVSDPGIMPIGGATVRLRADGSINVSAN
SVEIGQGNRGVLRIVAQKMLRQPLRMISVSEPDTLLAPYDWGTGASRSTVIIGLAVQMAC
EDILRQIGETAATVLGGSPEDYQLEEGRIEGPAGSISILELLRRFNGMSAGEFLGVGRVN
SETKNGAFKLAPLFWETGAGACEIEVDEGTGAIRLVRVGGAADLGYVMNPKAAEGQDEGA
MVMGLGHTLFEEYVYEDGQVVNGTLFDYRVPTMEDAPFHVGTVLIESLDGPGPFGSRGGG
EGAILPVAPAVANALFQGWGVRIKDLPLTPERVWRALKAAKAAKET