Protein Info for ABID97_RS27840 in Variovorax sp. OAS795

Annotation: acyl-CoA dehydrogenase C-terminal domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 592 PF12418: AcylCoA_DH_N" amino acids 2 to 23 (22 residues), 31.6 bits, see alignment (E = 4.1e-11) PF02771: Acyl-CoA_dh_N" amino acids 41 to 157 (117 residues), 42.7 bits, see alignment E=2e-14 PF02770: Acyl-CoA_dh_M" amino acids 162 to 271 (110 residues), 56.3 bits, see alignment E=8.9e-19 PF00441: Acyl-CoA_dh_1" amino acids 281 to 449 (169 residues), 84.2 bits, see alignment E=3.4e-27 PF08028: Acyl-CoA_dh_2" amino acids 298 to 442 (145 residues), 37.7 bits, see alignment E=7.2e-13 PF12806: Acyl-CoA_dh_C" amino acids 469 to 586 (118 residues), 108.9 bits, see alignment E=5.8e-35

Best Hits

KEGG orthology group: None (inferred from 91% identity to vap:Vapar_5356)

Predicted SEED Role

"Acyl-CoA dehydrogenase (EC 1.3.8.7)" (EC 1.3.8.7)

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 1.3.8.7

Use Curated BLAST to search for 1.3.8.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (592 amino acids)

>ABID97_RS27840 acyl-CoA dehydrogenase C-terminal domain-containing protein (Variovorax sp. OAS795)
MTYQIPLRDIQFVLHELLQVPAMLEACGQPELDGETIDQVLTAAGQFASEVIAPLNGPGD
AHGCSMPSPGVVLTPPGFKKAYDEFTKNGWPGLACSPEFGGQGFPSVVANAVYEVFGGAN
MAWASYPGMSHATYVNVSANGSDEQKALYLPKIASGEWAGTMCLTEPNAGTDLGLMRTRA
VVQPDGSYSITGSKIFISGGEQDLTGNIMHLVLARLADAPPGVKGISLFIVPKFIPDANG
AAGARNGVVCGSIEHKLGIHGNSTCTINFDGATGWLLGAPNKGLAGMFVQMNHMRVLVGM
IAIGLMEAAYQKALAYAKDRLQGRTSGARSSGEAADPIIEHADVRRMLLTQKANIEGARA
LALWTAQLSDLQRLHPDAARRNETAELLGLLTPLVKALSSDLAVEGTLLAMQVFGGHGYI
RENGVEQHLRDVRIVGLYEGTNGVQAMDLLGRKVLADQGRQMGVFLDMAGAFAETCGPRE
AMREFSEPLAALAADIRQLTGELVATSAHDPHAAGAAAAPYLRLVGHLALAWTWARMAEV
ALRNADSTDPIYASKIATARFYFQRLLPQTAALCGEIRAGSSALMEPAVDLF