Protein Info for ABID97_RS27585 in Variovorax sp. OAS795

Annotation: branched-chain amino acid ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 367 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details PF13458: Peripla_BP_6" amino acids 27 to 359 (333 residues), 195.7 bits, see alignment E=2.6e-61 PF13433: Peripla_BP_5" amino acids 29 to 344 (316 residues), 76.2 bits, see alignment E=4.2e-25 PF01094: ANF_receptor" amino acids 47 to 361 (315 residues), 91.2 bits, see alignment E=1.1e-29

Best Hits

Swiss-Prot: 47% identical to LIVB1_BRUSU: Leu/Ile/Val-binding protein homolog 1 (BR1785) from Brucella suis biovar 1 (strain 1330)

KEGG orthology group: K01999, branched-chain amino acid transport system substrate-binding protein (inferred from 62% identity to app:CAP2UW1_2547)

Predicted SEED Role

"Branched-chain amino acid ABC transporter, amino acid-binding protein (TC 3.A.1.4.1)" in subsystem ABC transporter branched-chain amino acid (TC 3.A.1.4.1) (TC 3.A.1.4.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (367 amino acids)

>ABID97_RS27585 branched-chain amino acid ABC transporter substrate-binding protein (Variovorax sp. OAS795)
MHPSQRIAAPLLALAALFAPAVASADILVGVAGPMSGQYASGGEQMRNGVEAAVAAINAA
GGVLGQKLKVEVGDDVCDPKQAVAVANAMVNKKVSAIVGHYCSSSSIPASEVYSEAQVPM
ITISTNGKVTDRGLKNVFRITGRDDQEGVVAADYIVRKFAGKKIAVIDDKSAFGKGQADI
VAKYLADHKNAPVLRESITAGEKDYTALVSKLKAGGVDAMFYGGYYTELGLILRQSSQGG
LKLAVMSGNTSTSAELATAAGSAIDGLLFTFYPDPRKYPASAEIVKRFRDNKIEPDGYVL
FCYAAVQVYAQALQKAGSLRYADVQKALAGGSFDTVLGKVAFDAKGDPKDPGFVVYQWKG
NQYDLAH