Protein Info for ABID97_RS25240 in Variovorax sp. OAS795

Annotation: SprT family zinc-dependent metalloprotease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 317 PF01863: YgjP-like" amino acids 94 to 310 (217 residues), 180 bits, see alignment E=3e-57

Best Hits

KEGG orthology group: K07043, (no description) (inferred from 87% identity to vap:Vapar_4740)

Predicted SEED Role

"Putative predicted metal-dependent hydrolase" in subsystem Restriction-Modification System

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (317 amino acids)

>ABID97_RS25240 SprT family zinc-dependent metalloprotease (Variovorax sp. OAS795)
MDLFEGLGNEFAPAKPAAPRPRKVGKKAAPPGPSPSVPAESQQDKSREAGTALPAVPLRD
TLALASFVHPQATRETVLGSARVAYEFKRGKRKTIGFLVGAEGLSVRAPRWVTLRDVDAA
IKEKSDWILRKLLETQQRHARVEATRIAWKDGAQFPFMGETVMIRLDPKHGFASVGGTLD
ASDDGHGPRILRLAVAQNAEASQIRDAAQAWLMRQARRLFIERLDHFAPRLGVRWKKLSL
SNAATRWGSASADGSIRLNWRLIHFRLPVIDYVVAHELAHLRVMDHSHRFWETVESVVPD
YDRLRQQLKDEAVPRWS