Protein Info for ABID97_RS20000 in Variovorax sp. OAS795

Annotation: circularly permuted type 2 ATP-grasp protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 917 PF14403: CP_ATPgrasp_2" amino acids 158 to 542 (385 residues), 469.2 bits, see alignment E=1.4e-144 PF04174: CP_ATPgrasp_1" amino acids 158 to 485 (328 residues), 321.4 bits, see alignment E=9.1e-100 PF04168: Alpha-E" amino acids 591 to 905 (315 residues), 196.6 bits, see alignment E=1.2e-61

Best Hits

KEGG orthology group: None (inferred from 93% identity to vap:Vapar_3406)

Predicted SEED Role

"Protein containing domains DUF404, DUF407, DUF403"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (917 amino acids)

>ABID97_RS20000 circularly permuted type 2 ATP-grasp protein (Variovorax sp. OAS795)
MEPLNESLFDAQALEFPAALASALAPAALPGHFDELRGQATPTALARPAMGLPPMAPMPP
LLYDAAAERPASGPATQSQAQSQSQAQAPAQASQPSQEKPPLTPSWNAFFDQLGPGGFGD
LPRRAVSLERQIRDNGVTYNVYADANGPQRPWSLDLFPLIVSPESWNQIEAGVLQRVRVL
DRVMADVYGPQQLLAEGLLPAALVRGHPGYLRALHGVKPPGDTWLHIAAFDLARGPDGNW
WVVSQRTQAPSGLGYLLENRLAITRQFPQAFEALHVQRLAATYSAMMDGLQHMCPAGVPP
HIALLTPGPYNETYFEHAYLARYLGVTLVEGSDLTVRDQRLYLKTLQGLRPVHGLIKRLD
DQFLDPLELRPDSTLGVPGLLQAIRAGNVLVANMPGSAFLESPALLGFLPGLARRLIGEK
LKLPALPTWWCGERAALEAVLPQLGDCAIKPTYPGSDGQTSFDAVLGSELSRRQLDEWAG
RIVREGEAHTIQSYLPLSQMPTWANDLGPGHIAPRAVLLRVFAVSDGAQSWRVLPGGLAR
LAGRDAQIASMQRGGSSADVWVQTHGEVDRTTLLQPHATPASLARHRAPVTSRAAENMFW
LGRYTERAENAVRLARLTLNLLGSEDQSSRPLLDWLHRMALRNALVPAGVPSAPQSRRVF
ERALIAELGDVEHGGSVGFSLLCIRQAAAAVRERLSQDNWNQIVRAEAEFLRRAAEQAGE
GSFATGAALRALETASTALAAMTGAQTDRMTRDDAWRLLSIGRHIERLGFLASALEAGFD
GGAVHEVSGFEAMVALFDSTITFHARYQQRRDVATLVDLLVLDAENPRSLAWVTQTLRGR
IARLAGSAPGKLTALSYELPDPATWTLEHLCAPGADASYPALVELLASCETAAYHVSDAI
GTRYFTLTSESLRSVGA