Protein Info for ABID97_RS15490 in Variovorax sp. OAS795

Annotation: FMNH2-dependent alkanesulfonate monooxygenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 389 PF00296: Bac_luciferase" amino acids 1 to 331 (331 residues), 284.2 bits, see alignment E=7.6e-89 TIGR03565: alkanesulfonate monooxygenase, FMNH(2)-dependent" amino acids 2 to 355 (354 residues), 616.3 bits, see alignment E=6.8e-190

Best Hits

Swiss-Prot: 96% identical to SSUD_VARPS: Alkanesulfonate monooxygenase (ssuD) from Variovorax paradoxus (strain S110)

KEGG orthology group: K04091, alkanesulfonate monooxygenase [EC: 1.14.14.5] (inferred from 96% identity to vap:Vapar_2976)

MetaCyc: 67% identical to alkanesulfonate monooxygenase subunit (Pseudomonas putida DS1)
RXN-18086 [EC: 1.14.14.34]

Predicted SEED Role

"Alkanesulfonate monooxygenase (EC 1.14.14.5)" in subsystem Alkanesulfonate assimilation or Alkanesulfonates Utilization (EC 1.14.14.5)

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 1.14.14.5

Use Curated BLAST to search for 1.14.14.34 or 1.14.14.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (389 amino acids)

>ABID97_RS15490 FMNH2-dependent alkanesulfonate monooxygenase (Variovorax sp. OAS795)
MQIFWFLPTHGDSRYLGTSEGSRPVDLAYLQQIAGAADNLGYEGVLIPTGRSCEDPWVIA
SSLIGATKNLKFLVAVRPGLHQPSLAARMAATFDRLSGGRLLVNLVTGGDQAELEGDGVY
LDHAARYEQSAEFIRIWREILARSHDGLGFDYEGRHLSVKGAKLLYPPVQNPYPPVWFGG
SSPAAHELAAEQVDAYLTWGEPPAEVARKIADVRNRAARKGRTVQFGIRLHVIVRETEDA
AWKAAEELISRVDDETVIRAQAAFARMDSEGQRRMAALHAGGAKRSRADLEISPNLWAGV
GLVRGGAGTALVGDPQTVAARIEEYASLGLDKFILSGYPHLEEAYRFAELVFPLLSRKAQ
ARLAGGSLSGPFGEVVANLDAPSRLVSQS