Protein Info for ABID97_RS15325 in Variovorax sp. OAS795

Annotation: FAD-dependent oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01266: DAO
  • amino acids 9 to 337 (329 residues), 139 bits, E=2.9e-44

Best Hits

KEGG orthology group: K03153, glycine oxidase [EC: 1.4.3.19] (inferred from 91% identity to vap:Vapar_2398)

Predicted SEED Role

"Glycine oxidase ThiO (EC 1.4.3.19)" in subsystem Thiamin biosynthesis (EC 1.4.3.19)

MetaCyc Pathways

• superpathway of thiamine diphosphate biosynthesis II (9/11 steps found)
• glyphosate degradation II (1/1 steps found)
• thiazole component of thiamine diphosphate biosynthesis II (5/7 steps found)
• butanol and isobutanol biosynthesis (engineered) (3/8 steps found)

KEGG Metabolic Maps

• Thiamine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.4.3.19

Protein Sequence (363 amino acids)

>ABID97_RS15325 FAD-dependent oxidoreductase (Variovorax sp. OAS795)
MSLPFRSAAILGAGLMGRLLAVTLAQAGCKVALFEAGSPEAEGAAARVAAAMLAPLAESA
VAPVSVVRMGHHALSRWPELLAPLAQPVFLQREGTLVLWHRQDAAEAARLARVLARTGAE
VPELAPIQALDGAGIAALEPSLGQRFAQGLFLPGEGQLDNRALLSALLATLQASPQVTLH
WQSPRAPADFAPGAPGQPDWVIDCRGLGARPQWSALRGVRGEVIRVHAPEVALQRPTRLV
HPRYPLYIAPKPGGVFVIGATEIESDDMSPASVRSTLELLSAAYAVHSGFAEARILEIAT
QCRPTLPDNLPAIRQPQPRVLQINGLYRHGFMIAPAVLDAAMELLVHGRSTLAQDLGLNT
SEA