Protein Info for ABID97_RS11750 in Variovorax sp. OAS795

Annotation: trimeric intracellular cation channel family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 205 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details transmembrane" amino acids 31 to 49 (19 residues), see Phobius details amino acids 64 to 82 (19 residues), see Phobius details amino acids 88 to 109 (22 residues), see Phobius details amino acids 115 to 136 (22 residues), see Phobius details amino acids 148 to 166 (19 residues), see Phobius details amino acids 172 to 193 (22 residues), see Phobius details PF03458: Gly_transporter" amino acids 6 to 78 (73 residues), 69.6 bits, see alignment E=8.4e-24 amino acids 91 to 164 (74 residues), 76.9 bits, see alignment E=4.3e-26

Best Hits

Swiss-Prot: 48% identical to Y1240_HAEIN: UPF0126 membrane protein HI_1240 (HI_1240) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: None (inferred from 72% identity to dar:Daro_3213)

Predicted SEED Role

"putative membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (205 amino acids)

>ABID97_RS11750 trimeric intracellular cation channel family protein (Variovorax sp. OAS795)
MMMTFIYVVAIVAEAMSGALAAGRRSMDIFGVAVIAFVTALGGGTVRDVILGNFPIGWTK
HPEYVGLVIAAGLFTTLIAAHMHKLKRLFLALDAMGLVAFSLIGCDIALRLDYALPVVVM
AGMITGICGGVVRDVLCNQIPVVFQRELYASVSLVVCCLFLLLRSFDLNPALNTTFSFAV
GLALRMQAIRFGWKLPTFSYQGRWE