Protein Info for ABID97_RS10490 in Variovorax sp. OAS795
Annotation: tannase/feruloyl esterase family alpha/beta hydrolase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K09252, feruloyl esterase [EC: 3.1.1.73] (inferred from 92% identity to vap:Vapar_1752)Predicted SEED Role
"Tannase and feruloyl esterase"
MetaCyc Pathways
- cellulose and hemicellulose degradation (cellulolosome) (1/3 steps found)
Isozymes
Compare fitness of predicted isozymes for: 3.1.1.73
Use Curated BLAST to search for 3.1.1.73
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (565 amino acids)
>ABID97_RS10490 tannase/feruloyl esterase family alpha/beta hydrolase (Variovorax sp. OAS795) MAIPKTLIRGGAMAASAVLLAACTTTGPQSLALGANPAAACAALVAPVAPAAIGLPSGAA TIDSATLVPASALAVAERGPSPASRITPPTPAHCKVLGRIAPLDANAPPILFQVNLPLAW NGRSVQYGGGGFNGVLITGLSLVPAGRFDQPTPLAQGYVTYGTDSGHQNVAGQPPQAFAL NDEALVNFAHASYKKVRDVAVALMQRAYGQAPQKLYFVGSSEGGREALTMAQRYPQDFDG IFSRVPVINWTGLQHAGTRNGIATFGEGWLRPAQVQLVHNAVLAACDAADGAADRIVSNP VACLQHFDPATLRCAAGTSGDNCLNDAQVQAVRTLRSPWRSPVPLANGVTAYPGWGIGGE GTPAFASMGGWNAWWTGTSAPTVPPQQSNGIAWFYGSGALQYFYARNPSLDVRNYRAEDF AARIATVSQLMDSTNPDLAAFAARGGKLLVLEHMADYAQSPFAGILYYESVVARMGRDST DRFMRLYTAPGVDHVGSGAPANVDMLGALADWVERGRAPAGLQLAEQGVQPPFRTVRARP LCEWPLWPRFTGGDVSQAASFQCSR