Protein Info for ABID97_RS09890 in Variovorax sp. OAS795

Annotation: class I SAM-dependent methyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 531 PF13489: Methyltransf_23" amino acids 35 to 153 (119 residues), 41.7 bits, see alignment E=3.7e-14 PF13847: Methyltransf_31" amino acids 48 to 155 (108 residues), 38.4 bits, see alignment E=3.7e-13 PF13649: Methyltransf_25" amino acids 50 to 147 (98 residues), 48.2 bits, see alignment E=5e-16 PF08241: Methyltransf_11" amino acids 51 to 150 (100 residues), 30.7 bits, see alignment E=1.4e-10 PF08242: Methyltransf_12" amino acids 51 to 148 (98 residues), 48.9 bits, see alignment E=3.3e-16 PF10119: MethyTransf_Reg" amino acids 219 to 302 (84 residues), 92.9 bits, see alignment E=6e-30 PF21782: PKMT_2nd" amino acids 444 to 528 (85 residues), 59.5 bits, see alignment E=1.3e-19

Best Hits

KEGG orthology group: None (inferred from 80% identity to vap:Vapar_1624)

Predicted SEED Role

"Methyltransferase (EC 2.1.1.-)" (EC 2.1.1.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.1.1.-

Use Curated BLAST to search for 2.1.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (531 amino acids)

>ABID97_RS09890 class I SAM-dependent methyltransferase (Variovorax sp. OAS795)
MPDSLTSTLTSYYDAVPYESHPFPQTAVEHLEAIAYLFGLQAPPPASARVLELGCASGGN
LIPFAARHPQASALGLDLSKVQVAQGAGAISRAALANVALRVFDLAQVDASFGQFDYIVC
HGVYSWVPGPVQDAILRICCENLAPDGVAYVSYNVYPGWKAREIVRDAMILRGGPRDTPE
EKLSYARGMLEFLEQSARPDSVLKKTLDETMPIVRRSSSDYLLHEFLEPCNAPCYFKEFA
ARAEARGLAYLGDAEPSSMFVQNYGDKVREPLLRECGGSQVLMEQYLDFLVNRIFRQTLL
VKQGRGGDIRFRLDPVRVRGLEYAGLFSPADGGALTLDAREQPCKALRNITVTLRLPVHK
ALAQALDNRYPATASPEALIAAVTGATGEPRATVEPLVMSMLEELLILGAVRIRRTPVHV
AAEVSAWPVALPSVRTAPGIALSAGNSASACNQWHESVALTALERSLLPLLDGAHSHDAL
ADHLVNEVRAERLRFVHGDQPLADAPALKQFALKQVALGLQDLWRKALLVA