Protein Info for ABID97_RS07590 in Variovorax sp. OAS795

Annotation: formate dehydrogenase accessory sulfurtransferase FdhD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF02634: FdhD-NarQ
  • amino acids 40 to 279 (240 residues), 234.7 bits, E=6.6e-74

Best Hits

KEGG orthology group: K02379, FdhD protein (inferred from 97% identity to vap:Vapar_4057)

Predicted SEED Role

"Formate dehydrogenase chain D (EC 1.2.1.2)" in subsystem Formate hydrogenase (EC 1.2.1.2)

MetaCyc Pathways

• formate oxidation to CO₂ (1/1 steps found)
• oxalate degradation VI (2/4 steps found)
• oxalate degradation III (2/5 steps found)
• superpathway of C1 compounds oxidation to CO₂ (7/12 steps found)
• purine nucleobases degradation II (anaerobic) (15/24 steps found)
• purine nucleobases degradation I (anaerobic) (6/15 steps found)

KEGG Metabolic Maps

• Glyoxylate and dicarboxylate metabolism
• Methane metabolism

Isozymes

Compare fitness of predicted isozymes for: 1.2.1.2

Use Curated BLAST to search for 1.2.1.2

Protein Sequence (291 amino acids)

>ABID97_RS07590 formate dehydrogenase accessory sulfurtransferase FdhD (Variovorax sp. OAS795)
MTTPVGPLPLPRLTQARAALTREVEVVDEHGARGTVSIPAERDLTVYVDRRELVTLMTLG
AQPELLVLGYLLNQRLIESASDVESVTVDWEVGGAAVKTHAGIDRIEERTARKVVTTGCG
QGSVFGDLMADIDQLELPPTRMTQAQLYALVNAIRLQESTYKSAGSVHGCALFTLEPGGT
EATMHCFVEDVGRHNAIDTIAGWCAMQPPGALAGDRVFYTTGRLTSEMVIKSAQMGVPIV
VSRSGITQMGHEVATRVGLCAIGRATNRHFVCYAGVDRLVLQPELARRSPA