Protein Info for ABID97_RS07085 in Variovorax sp. OAS795

Annotation: HAD family phosphatase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 213 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF00702: Hydrolase" amino acids 109 to 185 (77 residues), 37.9 bits, see alignment E=4e-13 PF13419: HAD_2" amino acids 122 to 189 (68 residues), 28.4 bits, see alignment E=2.5e-10 TIGR01509: HAD hydrolase, family IA, variant 3" amino acids 134 to 190 (57 residues), 52.3 bits, see alignment E=3.7e-18 PF13242: Hydrolase_like" amino acids 148 to 190 (43 residues), 27.3 bits, see alignment 4.2e-10

Best Hits

KEGG orthology group: K07025, putative hydrolase of the HAD superfamily (inferred from 85% identity to vap:Vapar_1100)

Predicted SEED Role

"HAD superfamily hydrolase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (213 amino acids)

>ABID97_RS07085 HAD family phosphatase (Variovorax sp. OAS795)
MNVVFDLGAVLLAWEPTRLVQAHLPEHAPTELAAAALGRALFHHDDWLCFDCGTRSLEDA
IARMSQRLSLPAARLGDMLGDLGERLEAIPVTLELLQGLFARRDAGEALRLYYLSNMPSP
YARAIERRHGFMRRFDGGVFSGDVKFIKPNREIYELLAVRHALDPQQTVFIDDSAANVEA
ARAFGWHAIHCTHPAALAAQLGRYLPSAAAIGR