Protein Info for ABID97_RS06750 in Variovorax sp. OAS795

Annotation: lytic murein transglycosylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 441 signal peptide" amino acids 1 to 38 (38 residues), see Phobius details PF13406: SLT_2" amino acids 72 to 362 (291 residues), 377 bits, see alignment E=6.3e-117 TIGR02283: lytic murein transglycosylase" amino acids 72 to 365 (294 residues), 365.7 bits, see alignment E=8.9e-114 PF01471: PG_binding_1" amino acids 383 to 438 (56 residues), 51 bits, see alignment 1.4e-17

Best Hits

KEGG orthology group: None (inferred from 82% identity to vap:Vapar_1030)

Predicted SEED Role

"Membrane-bound lytic murein transglycosylase B precursor (EC 3.2.1.-)" in subsystem Peptidoglycan Biosynthesis (EC 3.2.1.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.-

Use Curated BLAST to search for 3.2.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (441 amino acids)

>ABID97_RS06750 lytic murein transglycosylase (Variovorax sp. OAS795)
MHSTSILFPLFPYSRSFARLASSGAVAVLLAACASTPSTPVQTPSGSATSARPAPSMPAQ
APAGDAAIAQRFASWVADFRATARAQGISEATLRSALDPVQYLPRVIELDRAQPEFTRTV
WDYLDNAVTPQRIATGQEKLAQVRAEADAAAARYGVPPAVVVAIWGMESNYGANYGNTPV
IDALATLGFEGRREEWARGELIAALKILDSGDIARERMVGSWAGAMGQTQFLPSNFLAYA
VDADGDGRRDIWGSMPDVVATTANFLSRSGWQAGMPWGAELRLPAGFDFGRADMAVRQSS
AQWAVEGLRTIDGQPLPAFADGSVLLPAGARGPAFLVGPNFRAVLRYNNSINYALAVSLL
AQRLGGGPGVQAPWPRDMAALSRSQTIELQNALNQRGFATGTADGVMGPATRDGLRRYQR
SVGLPADGYPSAEVLQRLQQP