Protein Info for ABID97_RS05855 in Variovorax sp. OAS795

Annotation: acyl-CoA dehydrogenase C-terminal domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 598 PF12418: AcylCoA_DH_N" amino acids 3 to 35 (33 residues), 47.5 bits, see alignment (E = 4.3e-16) PF02771: Acyl-CoA_dh_N" amino acids 82 to 160 (79 residues), 42.1 bits, see alignment E=3.1e-14 PF02770: Acyl-CoA_dh_M" amino acids 165 to 273 (109 residues), 42.6 bits, see alignment E=1.7e-14 PF00441: Acyl-CoA_dh_1" amino acids 284 to 452 (169 residues), 71.7 bits, see alignment E=2.4e-23 PF12806: Acyl-CoA_dh_C" amino acids 475 to 593 (119 residues), 102.8 bits, see alignment E=4.5e-33

Best Hits

KEGG orthology group: None (inferred from 98% identity to vap:Vapar_0810)

Predicted SEED Role

"Acyl-CoA dehydrogenase (EC 1.3.8.7)" (EC 1.3.8.7)

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 1.3.8.7

Use Curated BLAST to search for 1.3.8.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (598 amino acids)

>ABID97_RS05855 acyl-CoA dehydrogenase C-terminal domain-containing protein (Variovorax sp. OAS795)
MPSYNPPVRDMQFVLHEVLNVADELKALPAHAETDADTINAVIEEAGKFAAEVTFPLNIS
GDEEGCTLDKTTHEVKTPKGFKDAYARYVEGGWPALSCDPAFGGQGLPFVVNQCLFEMLN
SANQAWTMYPGLSHGAYEALVAHGTEEQKKTYLPKLTTGEWTGTMCLTEPHCGTDLGLLR
TKAEPQPDGSYRITGSKIFISAGEHDMTDNIIHLVLARLPDAPKGSKGISLFVVPKYKVK
ADGSLGERNPIFCAGLEHKMGIHGNATAQIVIEGATGSLVGEPNKGLQAMFVMMNAARLG
VGNQSLGLTEVAYQNALAYAKDRVQMRSLSGVKAKDKEADPIIVHPDVRKMLLTAKAYAE
GGRALQIFCTLLLDKEHHHPDEKVRKDSGELVALLTPIVKAFITDNGHIATNACMQVFGG
HGFIKEWGMEQFVRDNRINMIYEGTNTIQSLDLLGRKVLGNNGASLKKFGKLVARLVEEE
GVNEKMAEFINPIAMLGDQLTKFTTEIGFKGFQNPDEVGAAAVDYLRVAGHFVFGYLFAR
MAQVALREIAAGNTDPFYVAKLQTARFYFAKLFPETATLMRTARAGSKVLMDTDAALA