Protein Info for ABID97_RS03270 in Variovorax sp. OAS795

Annotation: LacI family DNA-binding transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 343 PF00356: LacI" amino acids 11 to 58 (48 residues), 47.1 bits, see alignment 3.3e-16 PF00532: Peripla_BP_1" amino acids 69 to 315 (247 residues), 125.5 bits, see alignment E=5.9e-40 PF13407: Peripla_BP_4" amino acids 72 to 281 (210 residues), 63.4 bits, see alignment E=5.1e-21 PF13377: Peripla_BP_3" amino acids 177 to 337 (161 residues), 130.5 bits, see alignment E=1.3e-41

Best Hits

KEGG orthology group: K02529, LacI family transcriptional regulator (inferred from 95% identity to vap:Vapar_0131)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (343 amino acids)

>ABID97_RS03270 LacI family DNA-binding transcriptional regulator (Variovorax sp. OAS795)
MNTSPPASPVTIRDVARAAGVHVSTVSRALSPDKRSLISDEVLRVVEEAAQRLGYRPNRA
ASALRTGRTHTIGVLVPDITNAVFPPILQGIEASAAARGYFVFVTNVVDPALARPVLERM
LAQRVDGVILATATRDDPLVDFVAKAGMTAVLVNRADETGRLPAVVSDDRLAMKLAVDHL
VGLGHKRIAHLAGPQNIPTGVGRRLGVEQALRDHRMKPFRVVECASYSREAGAAAMRQML
QAGAAPQAVVCCNDLVALGAYDALREAGLRVPEHISITGHNDMPLVDMVDPPLTTIRLPH
RELGWRAAEMLFSEIDGQAMSASTVVLRPELVVRQSTGAPAGR