Protein Info for ABID97_RS00680 in Variovorax sp. OAS795

Annotation: elongation factor G

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 699 TIGR00484: translation elongation factor G" amino acids 1 to 697 (697 residues), 1208.9 bits, see alignment E=0 PF00009: GTP_EFTU" amino acids 9 to 286 (278 residues), 215 bits, see alignment E=1.7e-67 TIGR00231: small GTP-binding protein domain" amino acids 9 to 187 (179 residues), 118.8 bits, see alignment E=2e-38 PF03144: GTP_EFTU_D2" amino acids 328 to 395 (68 residues), 70.6 bits, see alignment E=3e-23 PF14492: EFG_III" amino acids 408 to 482 (75 residues), 116.3 bits, see alignment E=1.3e-37 PF03764: EFG_IV" amino acids 483 to 603 (121 residues), 163.2 bits, see alignment E=5.6e-52 PF00679: EFG_C" amino acids 606 to 691 (86 residues), 103.8 bits, see alignment E=1e-33

Best Hits

Swiss-Prot: 88% identical to EFG1_POLSJ: Elongation factor G 1 (fusA1) from Polaromonas sp. (strain JS666 / ATCC BAA-500)

KEGG orthology group: K02355, elongation factor G (inferred from 87% identity to aav:Aave_0335)

Predicted SEED Role

"Translation elongation factor G" in subsystem Translation elongation factor G family or Universal GTPases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (699 amino acids)

>ABID97_RS00680 elongation factor G (Variovorax sp. OAS795)
MSRKTPIERYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVHDGAATMDWMEQEQERG
ITITSAATTCFWKGMAGKFEEHRINIIDTPGHVDFTIEVERSMRVLDGAVMVYDAVGGVQ
PQSETVWRQANKYKVPRLAFVNKMDRTGADFLRVRQMMVDRLKANPVVIQIPIGAEEHFQ
GIVDLVKMKAIIWDEDKGVTFTYGEIPANLTDVCNEYREKLVEAAAEASEELMNKYLEGN
ELTEEEIKKAIRQRTIAGEIQPMLCGSAFKNKGVQAMLDAVIEYMPAPTDIPPVNGLDED
EAPVTRKADDSEKFSALAFKLMTDPFVGQLTFVRVYSGVLTKGDSVYNPVRGKKERIGRI
VQMHANNREEVNEIRAGDIAACVGLKEVTTGETLCDPAAIVTLERMVFPESVISQAVEPK
TKADQEKMGIALQRLAQEDPSFRVKTDEESGQTIIAGMGELHLEIIVDRMKREFGVEANV
GKPQVAYRETIRKTVEDAEGKFVRQSGGKGQYGHVILKLEPQEAGKGFEFVDAIKGGVVP
REYIPAVEKGVVEALTQGVLAGYPVVDVKVTLHFGSYHDVDSNEMAFKMAAIFGFKEGAR
KASPVILEPMMAVEVETPEDYAGNVMGDLSSRRGMVQGMDDMIGGGKSIKAEVPLSEMFG
YSTTLRSMSQGRATYTMEFKHYAEAPRNVAEAIVAARAK