Protein Info for ABID97_RS00165 in Variovorax sp. OAS795

Annotation: prolyl oligopeptidase family serine peptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 685 transmembrane" amino acids 551 to 565 (15 residues), see Phobius details PF02897: Peptidase_S9_N" amino acids 8 to 412 (405 residues), 88 bits, see alignment E=6e-29 PF00326: Peptidase_S9" amino acids 478 to 681 (204 residues), 135.7 bits, see alignment E=1.7e-43

Best Hits

KEGG orthology group: K01322, prolyl oligopeptidase [EC: 3.4.21.26] (inferred from 90% identity to vap:Vapar_4802)

Predicted SEED Role

"Prolyl endopeptidase (EC 3.4.21.26)" (EC 3.4.21.26)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.21.26

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (685 amino acids)

>ABID97_RS00165 prolyl oligopeptidase family serine peptidase (Variovorax sp. OAS795)
MTSNASTQTDEFLWLEDIDGAEQLAWARQQNDKTVQRYARSPAFERMEQGILEVLDSDAR
IPMVRKIGPFFYNFWRDKKNPKGLWRRTTLAGYREPQPAWETVIDLDALAEAEKENWVWH
GAQALQPGYKRCLVSLSRGGADADVVREFDLELRQFVTGGFTLPEAKSSVAWKDIDHLYV
ATDFGPGSMTSSSYPRIVKEWKRGTPLESAQVVYEGGMDDMTVSAWRDNTPGFERDFVSR
QMDFYDSETWLRGSDGRLAKIDVPDDANADITREWMLVEPRSPWTVAGTTYKPGSLLATR
FDDYMAGKREITVLFEPDESTALDDHSWTRHHLILNVMHDVVNKLEVLTPQPGSREWKRE
SLGGAPELSTIAAGAIDEDENDDYFLTVSGFLQPTTLYIGTIGQGEPEPLKDSPAFFDAS
RYRVSQHFATSKDGTRVPYFEIAPKNLQADGKNPTLQYAYGGFEISLQPSYSGSIGRAWL
EQGGVYVVANIRGGGEYGPRWHQAALQENRLRTCEDFAAVSQHLIARNITSPHHLGAMGG
SNGGLLMGNMLTLYPALYGAIVSEVALLDMKRYTQLSAGASWIAEYGDPEDPEEWAWIQA
FSPYENARPGQPYPPALFTTSTRDDRVGPVHARKMHAKLAAMGYDTSFYENIEGGHSAAS
DNKESAFMDALGYAYLWKHIGRTTA