Protein Info for ABI39_RS23175 in Phocaeicola dorei CL03T12C01

Annotation: glycoside hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 919 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF00295: Glyco_hydro_28" amino acids 599 to 761 (163 residues), 67.6 bits, see alignment E=5.3e-23

Best Hits

Predicted SEED Role

"Polygalacturonase (EC 3.2.1.15)" in subsystem D-Galacturonate and D-Glucuronate Utilization (EC 3.2.1.15)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.15

Use Curated BLAST to search for 3.2.1.15

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (919 amino acids)

>ABI39_RS23175 glycoside hydrolase (Phocaeicola dorei CL03T12C01)
MTRNAFWGLCIGLCLAGTQAIAQKMESKSIKTTDKTDSISFHIDGITEGESLFTVIGGPE
APVINAGMPGTEGIQGGFEGGSIVKIKGTYHMFPTERAGVKGMPAYHDRVKTRIGHWTST
DGVHWTRQSTILESSGVYALVHEDNPMNDRRSAIWSYMPVFSEENNRWYGFYLAYTTDKE
IAPNHSFGRIWRCESEKEGLEGIGGPYRDMGIIIEPGLDSQLWEGRQGVASFFPYKVDKG
WNAFISGAYPYETRADYPLKGGEKRKVWAVGLAESETLEGPWKRMGEEINPITSIHPQFV
ENPIVSKLPNGTYIAMFDGGPNYLNLPNRMGYTLSIDGKNWSKARYIAIDTKVKKWWTVM
RTPLCLIPEGDNVYTIVYTAWDDTRFHPIGMVKVKLNPEVLDKLTAELKPAIPYLNEVGA
QAMPRNIVPIKNAYFNMPQPKRPVFPDFIVNMKNKGMTEDAPITDLVNRTIAEVSKQGGG
TVVIPEGKWKSARIVLKSNVNLHLAKGAEIEFSGRAEDYLPAVFTRHEGVEIMGPAAFIY
ANGENNIAITGEGTIYGPSMDAEIRKRPNGASVVEKDVPWDMPIEQRIYDGMEGRTFYRP
KTISPINCTNVLIEGITMERSTLWNVVPIYCENVIIRGITVNSTKVPSGDGIDIESCKNV
LIEYCTLNCGDDCFTLKAGRAEDGLRVGKPTENVIIRYSLAQHGHGGITCGSETAGVIKN
LYVHDCVFDGTRTGIRFKTRRNRGGGSDNTYYERLRMINVGKAFTWDLLGSAYYMGELAA
RYPARKVNRLTPDVKNILIKDFIVESADQFFTANGIPEIPFNQVVIENGEIKCKKLIGAL
NDAAGFTMRKLTIESLHNDIHILDGKDILFEDIHFKLPSEEIRVNVEGKKSKNIIFKNIN
ANQEKVEYKKESPMRIEIK