Protein Info for ABI39_RS20040 in Phocaeicola dorei CL03T12C01

Annotation: S9 family peptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 743 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF00930: DPPIV_N" amino acids 103 to 452 (350 residues), 294.7 bits, see alignment E=1.2e-91 PF00326: Peptidase_S9" amino acids 541 to 738 (198 residues), 143 bits, see alignment E=1.5e-45

Best Hits

KEGG orthology group: K01278, dipeptidyl-peptidase 4 [EC: 3.4.14.5] (inferred from 99% identity to bvu:BVU_3876)

Predicted SEED Role

"Dipeptidyl peptidase IV"

Isozymes

Compare fitness of predicted isozymes for: 3.4.14.5

Use Curated BLAST to search for 3.4.14.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (743 amino acids)

>ABI39_RS20040 S9 family peptidase (Phocaeicola dorei CL03T12C01)
MTKKNLFTLVLCLFCLGTTTHAQHIPTLEEAVYGGLIKTEGGSNVSWMKDGERYSKIEKN
AEGAYEVTAYKAKDNSKEVLIPANMLLNPQTGKPISVRNFIFSEDNSKVLIYTNTRRVWR
YDTRGDYWVLNLKNGKLQQLGKSLPEATLMFAKFSPDASRVAYVSRNNIYVESLADGKIN
QLTQDGNNEIVNGTFDWVYEEEFNCRDGFRWSPDGQYIAYWQSDTQGTGWFDIINNVDSI
YPKIQRFPYPKAGTANSAVKVGYVSADGGNTTWLALPGDARNHYIPRMEFIPGCNELFIQ
QMNRAQNTNKVWIAKIGENTPVNIFTDQDAAWLETNDNVRWLKGNKYFTWESERDGWRHL
YRVSRDGKEIKPITQGAFDYIQEVGADMDKGFVYFIASPDNFTQRYLYQARLFGNGEVKR
LSPVDQSGQHRYIMSPSGKWAVHTFSNSETPPVIDMVSFPAHKSVRLITDNAKAKEQYKA
LGLQPKEFVKTRSGELELDAWMIKPVNFDPSKKYPVIIDVYGEPANATVQDVWSGGSLWH
QYLANLGYIIVSIENRGANAPRGREWRKCIYGEVGTFASEDQARGIQDLARQYSFIDTTR
IGITGWSGGGSQTLNSMFRYPDVFHTGIAIAFVADQRLYDTIYQERYMNTPQNNPEGYRK
GSPISYAAGLKGNLLLIHGTGDDNVHYQNCEMLVNELVRHGKIFSQISYPMRSHGIYEGE
GTSLHLRKTMADYWLKNLPAGGK