Protein Info for ABI39_RS15270 in Phocaeicola dorei CL03T12C01
Annotation: type I pullulanase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K01200, pullulanase [EC: 3.2.1.41] (inferred from 99% identity to bvu:BVU_3034)Predicted SEED Role
"Glycogen debranching enzyme (EC 3.2.1.-) / Pullulanase (EC 3.2.1.41)" in subsystem Glycogen metabolism or Trehalose Biosynthesis or Maltose and Maltodextrin Utilization (EC 3.2.1.-, EC 3.2.1.41)
KEGG Metabolic Maps
- Ascorbate and aldarate metabolism
- Glycosaminoglycan degradation
- Nucleotide sugars metabolism
- Ubiquinone and menaquinone biosynthesis
Isozymes
Compare fitness of predicted isozymes for: 3.2.1.-
Use Curated BLAST to search for 3.2.1.- or 3.2.1.41
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (664 amino acids)
>ABI39_RS15270 type I pullulanase (Phocaeicola dorei CL03T12C01) MNVRHVIWASIVSTTISCQSVKKEYNSFDEYPVREDALTEMEYSPAETKFSLWAPTAEEV RVLLFESGNEGSASNTFPMEMGENGTWTISIKEDLKGKFYTFNVKVNGKWLGDTPGIMAK AVGVNGKRAAVLDLRSTDPEGWENDVRPPLKNYADIMVYEMHHRDFSLDSVSGIQNKGKF LALTEQGTISSSGEKTGIDHLKELGITHVHLLPSYDYASVDETKLDKAQYNWGYDPQNYN VPDGSYSTDPYKPDVRIREFKQMVQALHKAGIRVVLDVVYNHTFNTDESNFERTVPGYFY RQTKDGQWANGSGCGNETASDRAMMRKYMIESILYWINEYHIDGFRFDLMGIHDIETMNE IRAAIDKIDPSIFMYGEGWAASSPQLEADKLAMKANVEKMPRIAAFSDEMRDGLRGGWDD DTKGAFLVGEPGHEMSIKFGVVGAIEHPQVISDSVNYSKKPWALQPTQMISYVSCHDDMC LADRLKATMPDASVEELAALQKLAETFVFTSQGVPFIFAGDEMMRDKKGVHNSYNSPDSI NTIDWKNKTVHKDVFEYVKGLIAMRKAHPAFRMGDADMVRRQLEFLPVKNTNVVAFILKD NANGDSWKNIIVALNSRAEPVKLDIPSGKYTVICKDGKINMKGLGQVSGAELMVPARSAM IIHQ