Protein Info for ABI39_RS14910 in Phocaeicola dorei CL03T12C01
Annotation: hydroxylamine reductase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 66% identical to HCP_BACFN: Hydroxylamine reductase (hcp) from Bacteroides fragilis (strain ATCC 25285 / DSM 2151 / JCM 11019 / NCTC 9343)
KEGG orthology group: K00378, hydroxylamine reductase [EC: 1.7.-.-] (inferred from 97% identity to bvu:BVU_2981)Predicted SEED Role
"Hydroxylamine reductase (EC 1.7.-.-)" in subsystem Nitrosative stress (EC 1.7.-.-)
Isozymes
No predicted isozymesUse Curated BLAST to search for 1.7.-.-
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (552 amino acids)
>ABI39_RS14910 hydroxylamine reductase (Phocaeicola dorei CL03T12C01) MENNMFCFQCQETAKGFGCTLKGVCGKNATTARTMDLLLFVVRGISVVADQLRQHSLPVK KDVDNFIVDALFCTITNANFDDESIMKRIDKGLVIRNDLKHQAFAKDIPLPEADELNWKG SHDEYDAKAATVGVLREKNEDLRSLKELIMYGLKGMAAYLEHAMRLGHNDESIHRFMQNT IAQITTKSLSADELTVLALRTGEIGVRTMALLDKANTSSYGNPEITRVNIGTGTRPGILI SGHDLHDLEELLEQTKDSGVDVYTHGEMLPAHYYPAFKKYTHFVGNYGNAWWKQREEFTS FNGPILFTTNCIVPPLPNATYKERMFTTNSTGYPGCKHITADEKGHKDYTEIIETAKQCA APTEIEHGEIMGGFAHNQVFQLADKVVEAVKSGAIRKFIVMAGCDGRMRSRDYYTTFAEM LPKDTVILTAGCAKYRYNKLGLGDINGIPRVLDAGQCNDSYSLAVIALKLKEVFGLHDIN ELPIVYNIAWYEQKAVIVLLALLSLGIKEIHLGPTLPAFLSPNVTKVLVENFGVSGIGTV ESDMKKLGLMNE