Protein Info for ABI39_RS13920 in Phocaeicola dorei CL03T12C01

Annotation: HAMP domain-containing histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 669 signal peptide" amino acids 1 to 18 (18 residues), see Phobius details transmembrane" amino acids 27 to 49 (23 residues), see Phobius details amino acids 392 to 416 (25 residues), see Phobius details PF00512: HisKA" amino acids 446 to 511 (66 residues), 71.5 bits, see alignment E=4.7e-24 PF02518: HATPase_c" amino acids 557 to 664 (108 residues), 94 bits, see alignment E=7.9e-31

Best Hits

KEGG orthology group: None (inferred from 97% identity to bvu:BVU_2725)

Predicted SEED Role

"Two-component system sensor histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (669 amino acids)

>ABI39_RS13920 HAMP domain-containing histidine kinase (Phocaeicola dorei CL03T12C01)
MPIGCVLFLFYYLCSEFLEIILKEMRGLAIIFRFFMLLVLLLPVVALCPVKAETTLEGPI
LIVTSYNPETRSISDNLSAFMDEYRQRGGKYTPIIESMNCKNLSEAYLWKSRMASILGKY
KGKNRPSLVILLGQEAWSAYISQDTEIAKKTPSICGMVSVNGLVLPDDSIDTRVWEPESK
NIYTDFGDYNIVAGYVYEYDVDKNIELMRRFYPDMRRVAFISDNTYGGLSMQALVKKEME
KYPDLETIWLDGRTETFMEVSERMRRLPQNTCVLLGTWRVDCTESYVIGNTTYMLRDANP
TLPVFTIASVGLGHWALGGYTPEYHAVGKNIGAVTYDFLDKGDREGVDLVTIPGNYTFDI
KRLHEFKLDSLNLPQGAVLVNKTPSLYEQYKYWVIGVVSAFMFLIACFLIAIYYIIRINH
LKHHLEVSGEELLVAKEKAEESNRLKTAFLANMSHEIRTPLNAIVGFSSVLVSDDSSPAE
KAQYCDIIQKNSDLLLHLINDILDISRMESGKIKFVWEECDVVELCQTALSTAEYGRKTS
ALFLFETPVASLVIKTDAQRLKQVLINLLSNAAKFTPSGSIKLAIAIDKQHQQLELSVSD
TGCGIPSDKSDRVFERFEKLNEYSQGTGLGLAISRLIVENLGGKIWVDKDYTEGARFVFT
HPLTKKEKE