Protein Info for ABI39_RS11510 in Phocaeicola dorei CL03T12C01

Annotation: 50S ribosomal protein L11 methyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 281 PF06325: PrmA" amino acids 37 to 278 (242 residues), 173.8 bits, see alignment E=2.3e-54 PF05175: MTS" amino acids 120 to 217 (98 residues), 38.8 bits, see alignment E=3.1e-13 PF13489: Methyltransf_23" amino acids 132 to 217 (86 residues), 32.6 bits, see alignment E=2.5e-11 PF01135: PCMT" amino acids 133 to 216 (84 residues), 26.4 bits, see alignment E=2.3e-09 PF03602: Cons_hypoth95" amino acids 137 to 204 (68 residues), 24.5 bits, see alignment E=8e-09 PF13847: Methyltransf_31" amino acids 144 to 221 (78 residues), 39.9 bits, see alignment E=1.5e-13 PF13649: Methyltransf_25" amino acids 148 to 218 (71 residues), 32.9 bits, see alignment E=3.4e-11

Best Hits

Swiss-Prot: 97% identical to PRMA_BACV8: Ribosomal protein L11 methyltransferase (prmA) from Bacteroides vulgatus (strain ATCC 8482 / DSM 1447 / JCM 5826 / NBRC 14291 / NCTC 11154)

KEGG orthology group: K02687, ribosomal protein L11 methyltransferase [EC: 2.1.1.-] (inferred from 97% identity to bvu:BVU_2289)

Predicted SEED Role

"Ribosomal protein L11 methyltransferase (EC 2.1.1.-)" in subsystem Heat shock dnaK gene cluster extended or Ribosome biogenesis bacterial (EC 2.1.1.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.1.1.-

Use Curated BLAST to search for 2.1.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (281 amino acids)

>ABI39_RS11510 50S ribosomal protein L11 methyltransferase (Phocaeicola dorei CL03T12C01)
MKYLEVTFTTHPCNETVNDVVSALAGEIGFESFVECEAGVQAYIQQTLFDEEALKEMIAS
FPLPDTTVKYTIKEAEDKNWNEEWEKNFFQPIVIGDRCCIHSTFHKDTPKTEYEILINPQ
MAFGTGHHETTSSIISELLEADLKGKSVLDMGCGTSILAILASMRGANPVTAIDIDDWCV
NNSKDNIALNHIHNITVELGDANLLKGRKPFDVIIANINRNILLADLPHYAACMHPGSEI
FMSGFYMQDIPFIREKAESLGMEFVHHREKNNWAAVKFIMK